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Article
March 1915

MALIGNANT SYMPATHICUS TUMOR OF THE RIGHT SUPRARENAL

Author Affiliations

DES MOINES, IOWA

From the Pathological Institute of the German University in Prague, Prof. A. Ghon, director.

Arch Intern Med (Chic). 1915;XV(3):341-355. doi:10.1001/archinte.1915.00070210002001
Abstract

Through the work of A. Kohn,1 Wiesel2 and others, it is now definitely known that the medullary portion of the suprarenals is of nervous origin. According to Wiesel, certain cells from the neural canal become the building cells of the sympathetic system, and from them arise either chromoblasts, which accumulate in the paraganglia or wander into the suprarenals and later give rise to the chromaffinic cells, or neurocytes, which later develop into ganglion cells. Held3 states that these cells may also give rise to neuroglia. Now there have been observed tumors partly composed of ganglion cells and nerve fibers, and also new growths containing chromaffinic cells. But the most interesting of all these neurogenic tumors is a very malignant form which occurs apparently only in young children, and is most often found closely associated with the suprarenals. It has long been known that

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