That the regional lymphatic glands can filter out bacteria from an infected area has been conclusively shown with reference to numerous organisms by simultaneously cultivating them from both situations. More generalized invasion of glands in agonal and postagonal states is also a matter of common experience, many special studies having been made on this point, among which may be mentioned the recent ones of Southard and Canavan.1 In certain specific diseases, furthermore, the causal organisms may be present in the glands in association with the characteristic changes—notably in tuberculosis. Within the last two years, a great deal of interest has arisen in the latter type of gland infection, stimulated especially by bacteriologic studies of Hodgkin's disease, and other conditions associated with glandular enlargements of obscure origin.
Bunting and Yates,2 in 1913, almost simultaneously with Negri and Mieremet,3 isolated in pure culture by aerobic methods, from the lymph
BLOOMFIELD AL. THE BACTERIAL FLORA OF LYMPHATIC GLANDS. Arch Intern Med (Chic). 1915;XVI(2):197–204. doi:10.1001/archinte.1915.00080020051003