The coincidence of syphilis and Raynaud's disease has occasionally been observed. A few cases have been reported in which the diagnosis of Raynaud's disease was unwarranted, and in which we were dealing with a pure specific obliterative endarteritis ; in other cases in which the diagnoses are beyond question, the interdependence is very frail and uncertain, and we might more correctly speak of a simultaneous occurrence ; but several instances must be admitted in which the etiologic rôle of an acquired or inherited syphilis is extremely suggestive.
The following case is deemed worthy of record because confusing complications early in the course of the disease obscured the diagnosis, but chiefly because it adds another illustration to this curious group of cases.
—The history concerns a colored girl 7 years old, whose present illness began Feb. 5, 1914.
LISSER H. SYPHILIS AND RAYNAUD'S DISEASE. Arch Intern Med (Chic). 1915;XVI(4):509–516. doi:10.1001/archinte.1915.00080040003001