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Article
December 1915

THE URIC ACID SOLVENT POWER OF URINE CONTAINING HEXAMETHYLENAMIN (UROTROPIN) AS COMPARED WITH THAT OF NORMAL URINE

Author Affiliations

PORTLAND, ORE.

Arch Intern Med (Chic). 1915;XVI(6):1055-1066. doi:10.1001/archinte.1915.00080060167012
Abstract

It has been known for a long time that hexamethylenamin in aqueous solution has the power of putting into solution considerable uric acid. In illustration of this point we take occasion to report one of our own experiments. An excess of pure uric acid was added to five solutions of hexamethylenamin, and after being shaken they were kept in an incubator at body temperature over night. The uric acid in the filtrates from these was estimated by the usual method, the results being as follows :

  • 35.00 mg. of uric acid dissolved by 100 c.c. of 0.1 per cent.

  • 66.00 mg. of uric acid dissolved by 100 c.c. of 0.25 per cent.

  • 74.00 mg. of uric acid dissolved by 100 c.c. of 0.4 per cent.

  • 158.00 mg. of uric acid dissolved by 100 c.c. of 2.0 per cent.

  • 250.80 mg. of uric acid dissolved by 100 c.c. of 5.0 per cent.

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