[Skip to Content]
[Skip to Content Landing]
Article
January 1916

OBSERVATIONS ON THE ORIGIN AND STATUS OF THE SO-CALLED "TRANSITIONAL" WHITE BLOOD CELL

Author Affiliations

Resident Medical House Officer The Johns Hopkins Hospital BALTIMORE

From the Medical Clinic of The Johns Hopkins Hospital.

Arch Intern Med (Chic). 1916;XVII(1):1-12. doi:10.1001/archinte.1916.00080070006001
Abstract

Probably the status of no white cell of the blood is so uncertain as that of the so-called transitional cell. The original hypothesis of Ehrlich1 that this cell was a transition form between the large mononuclear and the polymorphonuclear has long since been discarded, although Sahli2 still adheres to the view that it is an intermediate stage between the myelocyte and the polymorphonuclear neutrophil. By many (Ehrlich,3 Emerson, Webster and Simon, in the latest editions of their text-books) it is believed to be a senile form of the large mononuclear. Pappenheim and Naegeli refute the hypothesis that this cell is a transitional form between the large mononuclear and the true polymorphonuclear neutrophil, the former regarding it as a promyelocyte in his scheme of blood-cell origin, while Naegeli, after first describing it as related to the myeloblast4 concludes that, together with the other mononuclears,

First Page Preview View Large
First page PDF preview
First page PDF preview
×