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February 1916

EXPERIMENTAL ALCOHOLIC CIRRHOSIS OF THE LIVER

Author Affiliations

IOWA CITY, IA.

From the Laboratory of Pathology and Bacteriology, Medical School, State University of Iowa.

Arch Intern Med (Chic). 1916;XVII(2):193-202. doi:10.1001/archinte.1916.00080080015002
Abstract

Ever since the experimental method has been used in pathology numerous attempts have been made to show the connection between cirrhosis of the liver as often seen in "steady drinkers" and alcohol as the causative factor. In this experimental work alcohol has been used subcutaneously, intravenously, by inhalation, and fed by mouth. Ethyl alcohol has been used by most all, but some have used amyl and methyl alcohol, while others have used mixtures of these, and still others have used various beverages, such as schnapps, brandy and absinthe. Rabbits, guinea-pigs, dogs, rats, mice, hens, cats, ducks and pigeons have been used as experimental animals. Dahlström,1 Duchek,2 Joffrey and Serveaux,3 von Baumgarten,4 and de Rechter,5 were among the first to carry out work along these lines, but with negative results. Ruge,6 Magnan,7 Kremiansky,8 Mairet and Cambermale,9 Afanassiew,10 v. Kuhlden,11

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