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September 1916


Author Affiliations


Arch Intern Med (Chic). 1916;XVIII(3):289-303. doi:10.1001/archinte.1916.00080160002001

The subject of dissociated jaundice has been discussed by a number of French physicians during the past five years. There have been in all about thirty articles on the subject published in French medical journals. A fairly complete bibliographic reference will be found in an article by Lemièrre, Brulè and Garban.1

In all the published articles there are several weak points for criticism. There was not sufficient correlative control of biliary elements in the plasma and urine. The adsorptive property of plasma for bile salts as well as bile pigment was not clearly perceived. As will be seen from our observations, the plasma may under some conditions, not yet clearly understood, retain a large amount of bile pigment and yield none of it to the kidney, although the kidney function may be perfectly normal. This adsorptive property of the plasma may hold bile pigment so firmly

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