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Article
December 1916

A STUDY OF LOW BLOOD PRESSURES NOT ASSOCIATED WITH TRAUMA OR HEMORRHAGE

Author Affiliations

chicago

From the Department of Pathology of Northwestern University Medical School.

Arch Intern Med (Chic). 1916;XVIII(6):848-855. doi:10.1001/archinte.1916.00080190133008
Abstract

In the course of studies on anaphylactic shock in the dog it was found that during the period of low blood pressure the pressor effect of nicotin may be greatly augmented at a time when epinephrin produces little or no result.1 Exactly similar reactions were found in peptone shock. Low blood pressures from hemorrhage are sharply distinguished from the above by the fact that in them, while the effect of nicotin may be exaggerated, that of epinephrin remains unchanged, as shown by Hoskins, Rowley and Rosser.2 It seems not improbable, therefore, that the mechanism of these phenomena may be different. It was suggested in connection with the study of anaphylactic shock that the augmented action of nicotin in that condition was due largely if not entirely to its effect on respiration. Further observations on this point are here reported, partly because they may have some bearing

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