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December 1917

THE NONPROTEIN CONSTITUENTS OF EDEMA FLUIDS

Author Affiliations

WITH THE ASSISTANCE OF A. S. MINOT, A.B. BOSTON

From the Chemical Laboratory of the Massachusetts General Hospital.

Arch Intern Med (Chic). 1917;XX(6):879-888. doi:10.1001/archinte.1917.00090060053004
Abstract

Although many investigations have been published regarding the proteins of edema fluids, the available data regarding their nonprotein constituents are exceedingly meager. In the standard and frequently copied analyses to be found in most textbooks these bodies are almost universally grouped together under the vague title of "extractives," and are to be found recorded under this general heading, together with the more elaborate analyses of the protein and inorganic constituents. By means of the micromethods which have come into general use during the past five years we now know, in a general way at least, the level at which the more common nonnitrogenous bodies are maintained in the blood in health and in disease. Investigations by modern methods along this line have, however, been extended in only a few instances1 to body fluids other than blood.

In view of this lack of available data it has seemed worth while to

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