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Article
January 1918

THE VALUE OF THE ATROPIN TEST IN THE DIAGNOSIS OF TYPHOID FEVER

Author Affiliations

MONTREAL, QUE.

From the Medical Clinic of the Royal Victoria Hospital, Montreal.

Arch Intern Med (Chic). 1918;XXI(1):1-13. doi:10.1001/archinte.1918.00090070010001
Abstract

With the recent publication of Marris'1 article on the use of atropin in the diagnosis of the enteric group of infections, we decided to avail ourselves of the opportunity that the medical services of this hospital offered. Therefore, within the last few months we have carried out the test according to Marris' technic on 109 patients, sixty-three of them suffering from typhoid, or paratyphoid B infections, and forty-six nontyphoid cases. In all, 305 tests were performed. The technic adopted is practically the same as that recommended by Marris, except that in most of our tests we have used one-thirtieth in place of onethirty-third grain of atropin sulphate. It is as follows:

On a fasting stomach the pulse rate is taken for ten consecutive minutes, while the patient rests quietly in bed. If the rate per minute remains practically constant, this is accepted as the average mean rate. Then one-thirtieth grain

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