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February 1918


Author Affiliations


From the medical Clinic of the Royal Victoria Hospital.

Arch Intern Med (Chic). 1918;XXI(2):216-230. doi:10.1001/archinte.1918.00090080043003

In this communication I wish to present certain observations recently made on three cases of acute nephritis that were admitted to the medical wards of the Royal Victoria Hospital. The patients were admitted at the onset of the condition and were studied until convalescence was well established. Two of the cases have been subsequently followed for a prolonged period. Observations were made as nearly simultaneously as possible by four methods which I believe give the most valuable data obtainable in kidney function studies. These four methods are (1) the test meal; (2) the estimation of the rate of excretion of urea; (3) the determination of the calculated and actual blood plasma chlorids in coordination with their rate of excretion, and (4) the phenolsulphonephthalein test.

The Nephritic Test Meal.  — The nephritic, or better the kidney function, test meal, as first advanced by Hedinger and Schlayer,1 and later elaborated by Mosenthal2

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