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Article
August 1918

SEROLOGIC LOCALIZATION OF ORGANIC BRAIN LESIONS

Author Affiliations

CHICAGO

From the Psychopathic Hospital of Cook County.

Arch Intern Med (Chic). 1918;XXII(2):234-244. doi:10.1001/archinte.1918.00090130110008
Abstract

During my work on dementia precox, the dialysis method of Abderhalden, slightly modified, proved to be of great value. Yet, as this method did not, for certain reasons, become very popular, I thought it imperative to show that if used properly it is quite reliable and more than that, it can be of great value in the clinical diagnosis of obscure cases.

It seemed advisable to attempt to localize by this method those gross brain lesions which could be verified either by an operation or by necropsy, or by unmistakable clinical evidence. The technic used in all experiments was a modification of the original method based on nearly 4,000 tests, was easy to perform, less complicated and perfectly reliable. The detailed description of this modification will be found in the latter part of this article.

In the cases in which the dialysis method has been used for the purpose of

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