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Article
November 1918

AN EXPERIMENTAL STUDY OF SERUM THERAPY IN TRICHINOSIS

Author Affiliations

DETROIT

Research Laboratory, Parke, Davis and Company.

Arch Intern Med (Chic). 1918;XXII(5):601-609. doi:10.1001/archinte.1918.00090160050005
Abstract

Salzer1 has published a study of trichinosis in which he claims to have secured beneficial results in man and in experiment animals by the use of serum from patients recovered from the disease. In this connection he also claims that injections of serum are prophylactic against trichinosis; that animals fed with infected meat within twenty-four hours after the administration of the serum might develop a mild form of trichinosis, but if fed at a later period would prove to be immune; and that if immune serum was mixed with infected meat and then fed to animals, the animals did not develop trichinosis, though the ingestion of the same meat without serum was invariably followed by the appearance of the disease. In two patients in the active stages of trichinosis the administration of the serum showed remarkable curative power; there was a decided drop in temperature within six hours and the

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