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This female infant was born after 37 weeks' gestation to healthy, unrelated parents. There was no family history of congenital abnormalities. Ultrasound examination performed at 13 weeks' gestation revealed no abnormalities. The mother refused to consent to any further echographic examination. An interview with the mother revealed discontinuous cocaine abuse during the first and second trimester of pregnancy. She denied cocaine abuse during the last trimester of pregnancy. Abuse of alcohol or of any other drugs during pregnancy was also denied.
Bellini C, Massocco D, Serra G. Prenatal Cocaine Exposure and the Expanding Spectrum of Brain Malformations. Arch Intern Med. 2000;160(15):2393. doi: