[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.205.176.107. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Editor's Correspondence
August 14/28, 2000

More Research Needed on the Association Between Diagonal Earlobe Crease and Coronary Artery Disease

Arch Intern Med. 2000;160(15):2393. doi:

I enjoyed the editorial on the association of asthma and obesity by Wilson and Irwin.1 The authors referred to the association between diagonal earlobe crease (DEC) and coronary artery disease (CAD) as an example of unrecognized or unappreciated cofactors.

Ever since the first report suggesting a connection between the DEC and CAD was published in 1973,2 numerous studies have been done throughout the world to investigate this association.3 Unfortunately, most studies have included elderly subjects. A large study from China involving 3155 persons4 concluded that DEC was a phenomenon of age and had no predictive significance for CAD in the aged population.57 Therefore, more studies with larger numbers of patients are required to either suggest or refute the possible association between asthma and obesity.

First Page Preview View Large
First page PDF preview
First page PDF preview
×