In a recent issue of the ARCHIVES, Aaron and colleagues1 examined the degree of overlap of 10 clinical conditions among patients with chronic fatigue syndrome (CFS), fibromyalgia (FM), and temporomandibular disorder (TMD) and healthy controls. They found that patients with CFS, FM, and TMD shared key symptoms, including generalized pain sensitivity, sleep and concentration difficulties, and bowel complaints. Patients with these conditions compared with controls were more likely to have irritable bowel syndrome, multiple chemical sensitivities, tension-type headache, and chronic low back pain. The authors indicate that because of the overlapping conditions and symptoms among patients with CFS, FM, and TMD, prospective studies that control for comorbidities will be needed to elucidate the pathophysiological mechanisms of these clinical syndromes.
Jay SJ. Tobacco Use and Chronic Fatigue Syndrome, Fibromyalgia, and Temporomandibular Disorder. Arch Intern Med. 2000;160(15):2393. doi: