Figure 1. Flow diagram showing selection of the studies for the meta-analysis.
Figure 2. Bar graph demonstrating the proportion of time spent in therapeutic anticoagulation across the included studies. INR indicates international normalized ratio. See the “Results” section for expansions of the study names.
Figure 3. Forest plots demonstrating pooled estimates of safety outcomes. All the estimates were derived from random-effects modeling. A, Stroke or non–central nervous system embolism. B, Myocardial infarction. C, All-cause mortality. D, Composite outcome. See the “Results” section for expansions of the study names. Diamonds indicate the overall summary estimate for the analysis (width of the diamond represents the 95% CI).
Agarwal S, Hachamovitch R, Menon V. Current Trial-Associated Outcomes With Warfarin in Prevention of Stroke in Patients With Nonvalvular Atrial FibrillationA Meta-analysis. Arch Intern Med. 2012;172(8):623-631. doi:10.1001/archinternmed.2012.121
Author Affiliations: Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.