Our intervention was associated with a significant decrease in nebulizer rates (as measured per month and normalized by total admissions) on a pilot medical ward. MDI indicates metered-dose inhaler; neb, nebulized bronchodilator therapy; RT, respiratory therapist.
Moriates C, Novelero M, Quinn K, Khanna R, Mourad M. “Nebs No More After 24”: A Pilot Program to Improve the Use of Appropriate Respiratory Therapies. JAMA Intern Med. 2013;173(17):1647-1648. doi:10.1001/jamainternmed.2013.9002
Nebulized bronchodilator therapies (“nebs”) are commonly used in the inpatient setting for the treatment of obstructive pulmonary symptoms. Nebs have equal efficacy when compared with metered-dose inhalers (MDIs) for patients with obstructive pulmonary symptoms1- 3 but are significantly more costly because they need to be directly administered by a respiratory therapist (RT). Unnecessary neb administration in the hospital also represents a missed opportunity to educate inpatients on proper use of their MDIs. Press et al4 found that while 86% of patients incorrectly administered their prescribed MDI, all were able to achieve mastery following instruction.
We created a program to decrease inappropriate neb administration, improve inpatient MDI teaching, and increase resident physician knowledge of appropriate respiratory therapies.
We performed a needs assessment at our 600-bed academic medical center and determined that over $1 million in direct costs were spent for administration of nebs to non–intensive care unit patients in the medical ward during fiscal year 2012.
Using direct cost financial data from our institution, we created a basic financial model. This model accounted for differences in direct pharmacy costs of neb and MDI medications, as well as RT time directly spent administering nebs and teaching MDI technique.
We assessed changes in resident physicians’ knowledge and attitudes regarding nebulizer and MDI use using preintervention and postintervention surveys. These anonymous surveys queried residents regarding the costs and efficacy of nebs vs MDIs, as well as their beliefs about MDI training adequacy.
We analyzed changes in knowledge (percentage answering a question correctly) before and after the intervention using χ2 statistics and Fisher exact tests as appropriate.
We implemented system changes, along with educational and promotional efforts, to encourage transitions of nebs to MDIs “within the first 24 hours of admission” (interventions and timeline are shown in the Figure). We monitored neb administrations on the pilot unit, our high-acuity medical ward, to determine the impact.
Prior to implementation, we averaged approximately 5 neb administrations per admission (for any cause) on our high-acuity medical ward. Our preliminary results demonstrate that overall nebs administered per month and number of nebs per patient fell by more than 50% on the pilot unit following our initial interventions (Figure). Based on our financial model, these improvements on only this single ward would save an estimated average of $20 827 in direct costs for our medical center each month, resulting in approximately $250 000 annually.
Prior to implementation, 49 of 74 eligible internal medicine residents (66%) completed our pretest survey. Thirty-two of 48 eligible residents (67%) completed the postintervention survey. At both baseline and following our intervention, residents were aware that albuterol neb treatments were more expensive than albuterol MDIs (82%, pretest; 94%, postintervention [P = .11]). Prior to the intervention 13 of the residents (26%) answered incorrectly that neb treatments were more efficacious than MDIs, in contrast to only 1 resident (3%) following exposure to our intervention (P < .01). At baseline, none of the residents agreed that “patients receive adequate inpatient MDI teaching”; however, this rate improved to 16% after the first 2 months of implementation (P < .01).
Our multifaceted intervention was associated with a simultaneous decrease in unnecessary neb treatments, an increase in evidence-based resident physician knowledge, and potentially an improvement in MDI patient education. This concurrent improvement in quality of care with a decrease in cost maximizes the “value equation” (defined as quality divided by costs). The approximately 50% decrease in nebs following our intervention highlights the degree of wasteful usage of this resource-intensive therapy previously on our pilot medical ward. Reducing inappropriate nebs represents a straightforward way for institutions to reduce health care costs through a simple intervention.
Our study has some limitations. Owing to the nature of our intervention and the significant crossover of our physicians, RTs, and nurses, it was not possible to create a control group at our medical center during this pilot study. Also, our financial model may overestimate our cost savings since RT time is a semifixed cost and our intervention has not yet led to a decrease in actual RT full-time equivalents. However, RT daily staffing is based on volume at our large hospital; thus, if the project is successfully scaled medical center–wide, then it would likely result in a decrease in daily RT staffing. Currently, this saved time is being repurposed for our RTs to perform other important job duties at our hospital, such as MDI training and smoking cessation counseling.
In conclusion, our pilot study illustrates that a multifaceted effort may be successful in dramatically decreasing the overuse of neb therapies on an inpatient medicine service. Reducing utilization of these resource intensive and unnecessary treatments may provide an ideal target for improving health care value.
Corresponding Author: Christopher Moriates, MD, Department of Medicine, University of California, San Francisco, 505 Parnassus Ave, M1287, San Francisco, CA 94143-0131 (email@example.com).
Author Contributions:Study concept and design: Moriates, Novelero, Quinn, Mourad.
Acquisition of data: Moriates, Novelero.
Analysis and interpretation of data: Moriates, Novelero, Khanna, Mourad.
Drafting of the manuscript: Moriates, Novelero.
Critical revision of the manuscript for important intellectual content: Quinn, Khanna, Mourad.
Statistical analysis: Khanna.
Obtained funding: Novelero.
Administrative, technical, and material support: Novelero, Quinn, Mourad.
Study supervision: Khanna, Mourad.
Published Online: July 22, 2013. doi:10.1001/jamainternmed.2013.9002.
Conflict of Interest Disclosures: None reported.
Additional Contributions: Theodore Omachi, MD, MBA (Department of Medicine, University of California, San Francisco), and Sumant Ranji, MD (Department of Medicine, University of California, San Francisco), contributed to the design and implementation of this project. They did not receive compensation.