[Skip to Content]
[Skip to Content Landing]
Article
February 1971

Contamination of Ultrasonic Nebulization Equipment With Gram Negative Bacteria

Author Affiliations

Oklahoma City

From the Department of Medicine, University of Oklahoma Medical Center, and Infectious Disease Section, Veterans Administration Hospital, Oklahoma City.

Arch Intern Med. 1971;127(2):228-232. doi:10.1001/archinte.1971.00310140056004
Abstract

Aerosol sampling of ultrasonic nebulizers (USN) during routine use revealed significant contamination by gram negative bacteria in each instance. Exposure of a sterile USN machine to a patient harboring Serratia in sputum resulted in heavy growth of Serratia in all parts of the USN after 48 hours. Acetic acid in a concentration of 0.25% was not effective in cleaning heavily contaminated machines, whereas 2% acetic acid for 30 minutes rendered the USN bacteria free. The USN are hazardous insofar as they contain water reservoirs in which certain gram negative organisms multiply rapidly. Hospitals must have a regular system of adequate cleaning and regular surveillance, preferably of aerosols produced, in order to prevent infecting patients requiring inhalation therapy.

References
1.
Ringrose RE, McKown B, Felton FG, et al:  A hospital outbreak of Serratia marcescens associated with ultrasonic nebulizer. Ann Intern Med 69:719-729, 1968.Article
2.
Reinarz JA, Pierce AK, Mays BB, et al:  The potential role of inhalation therapy equipment in nosocomial pulmonary infection. J Clin Invest 44:831-839, 1965.Article
3.
Moffett HL, Allan D, Williams T:  Survival and dissemination of bacteria in nebulizers and incubators. Amer J Dis Child 114:13-20, 1967.
4.
Cabrera HA:  An outbreak of Serratia marcescens and its control. Arch Intern Med 123:650-655, 1969.Article
5.
Phillips I, Spencer G:  Pseudomonas aeruginosa crossinfection due to contaminated respiratory apparatus. Lancet 2:1325-1327, 1965.Article
6.
Mertz JJ, Scharer L, McClement JH:  A hospital out-break of Klebsiella pneumonia from inhalation therapy with contaminated aerosol solutions. Amer Rev Resp Dis 95:454-460, 1967.
7.
Cross DF, Benchimol A, Dimond E:  The faucet aerator: A source of Pseudomonas infection. New Eng J Med 274:1430-1431, 1966.Article
8.
Burdon DW:  Contamination of disinfectants. Brit Med J 2:153-155,1967.Article
9.
Newsom SWB:  Hospital infection from contaminated ice. Lancet 2:620-622, 1968.Article
10.
Morse LJ, Schonbeck LE:  Hand lotions: A potential nosocomial hazard. New Eng J Med 278:376-378, 1968.Article
11.
Edmondson EG, Sanford JP:  Simple methods of bacteriologic sampling of nebulization equipment. Amer Rev Resp Dis 94:450-453, 1966.
×