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November 2016 - January 1908

Decade

Year

Issue

December 1, 2016, Vol 176, No. 12, Pages 1735-1884

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2016;176(12):1735-1737. doi:10.1001/jamainternmed.2015.4918
Viewpoint

Unfinished Business in Preventing Alzheimer Disease

Abstract Full Text
JAMA Intern Med. 2016;176(12):1739-1740. doi:10.1001/jamainternmed.2016.6310

This Viewpoint describes the US National Alzheimer Project Act and strategies to ensure that new medications will improve the lives of patients with asymptomatic Alzheimer disease.

Editorial

Announcing a New JAMA Internal Medicine Website

Abstract Full Text
free access
JAMA Intern Med. 2016;176(12):1749. doi:10.1001/jamainternmed.2016.6676

Lower Erythropoietin Doses and Medicare Payment ReformWin-Wins for Patients With End-stage Renal Disease

Abstract Full Text
JAMA Intern Med. 2016;176(12):1749-1751. doi:10.1001/jamainternmed.2016.6527
Original Investigation

Short-term Effects of High-Dose Caffeine on Cardiac Arrhythmias in Patients With Heart FailureA Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA Intern Med. 2016;176(12):1752-1759. doi:10.1001/jamainternmed.2016.6374

This randomized clinical trial evaluates the short-term effects of high-dose caffeine consumption vs placebo in patients with heart failure at increased risk for arrhythmic events.

Long-term Outcomes of the Western Australian Trial of Screening for Abdominal Aortic AneurysmsSecondary Analysis of a Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA Intern Med. 2016;176(12):1761-1767. doi:10.1001/jamainternmed.2016.6633

This randomized clinical trial assesses the influence of screening for abdominal aortic aneurysms in men aged 64 to 83 years on abdominal aortic aneurysm mortality.

Association of Industry Sponsorship With Outcomes of Nutrition StudiesA Systematic Review and Meta-analysis

Abstract Full Text
JAMA Intern Med. 2016;176(12):1769-1777. doi:10.1001/jamainternmed.2016.6721

This systematic review and meta-analysis examines whether food industry sponsorship of nutrition studies is associated with outcomes that favor the sponsor.

The Quality of Outpatient Care Delivered to Adults in the United States, 2002 to 2013

Abstract Full Text
JAMA Intern Med. 2016;176(12):1778-1790. doi:10.1001/jamainternmed.2016.6217

This cross-sectional survey study measures changes in outpatient quality and patient experience in the United States from 2002 to 2013 to determine whether efforts to improve outpatient quality have been successful.

State-Level Cancer Mortality Attributable to Cigarette Smoking in the United States

Abstract Full Text
JAMA Intern Med. 2016;176(12):1792-1798. doi:10.1001/jamainternmed.2016.6530

This study calculates the proportion of cancer deaths among adults 35 years and older that were attributable to cigarette smoking in each US state and the District of Columbia.

Receipt of Antibiotics in Hospitalized Patients and Risk for Clostridium difficile Infection in Subsequent Patients Who Occupy the Same Bed

Abstract Full Text
JAMA Intern Med. 2016;176(12):1801-1808. doi:10.1001/jamainternmed.2016.6193

This cohort study reports on the association of receipt of antibiotics by prior hospital bed occupants with increased risk for Clostridium difficile infection in patients subsequently occupying the same bed.

Association of Increasing Use of Mechanical Ventilation Among Nursing Home Residents With Advanced Dementia and Intensive Care Unit Beds

Abstract Full Text
JAMA Intern Med. 2016;176(12):1809-1816. doi:10.1001/jamainternmed.2016.5964

This cohort study assessed the association of the use of mechanical ventilation in nursing home residents with advanced dementia and the increasing number of intensive care unit beds among claimants in the Medicare Minimum Data Set.

Association Between Changes in CMS Reimbursement Policy and Drug Labels for Erythrocyte-Stimulating Agents With Outcomes for Older Patients Undergoing Hemodialysis Covered by Fee-for-Service Medicare

Abstract Full Text
JAMA Intern Med. 2016;176(12):1818-1825. doi:10.1001/jamainternmed.2016.6520

This cohort study assesses the association between changes in Centers for Medicare & Medicaid Services reimbursement policy and erythrocyte-stimulating agent drug labels with outcomes for patients undergoing hemodialysis.

Failure of Investigational Drugs in Late-Stage Clinical Development and Publication of Trial Results

Abstract Full Text
JAMA Intern Med. 2016;176(12):1826-1833. doi:10.1001/jamainternmed.2016.6008

This study assesses factors associated with regulatory approval or reasons for failure of investigational therapeutics in phase 3 or pivotal trials and rates of publication of trial results.

Nonfasting Mild-to-Moderate Hypertriglyceridemia and Risk of Acute Pancreatitis

Abstract Full Text
JAMA Intern Med. 2016;176(12):1834-1842. doi:10.1001/jamainternmed.2016.6875

This cohort study tests the hypothesis that nonfasting mild-to-moderate hypertriglyceridemia is associated with acute pancreatitis.

Invited Commentary

More Evidence That Caffeine Consumption Appears to Be Safe in Patients With Heart Failure

Abstract Full Text
JAMA Intern Med. 2016;176(12):1759-1760. doi:10.1001/jamainternmed.2016.6381

The Last (Randomized) Word on Screening for Abdominal Aortic Aneurysms

Abstract Full Text
JAMA Intern Med. 2016;176(12):1767-1768. doi:10.1001/jamainternmed.2016.6663

The Quest to Improve QualityMeasurement Is Necessary but Not Sufficient

Abstract Full Text
JAMA Intern Med. 2016;176(12):1790-1791. doi:10.1001/jamainternmed.2016.6233

The Case for a Concerted Push to Reduce Place-Based Disparities in Smoking-Related Cancers

Abstract Full Text
JAMA Intern Med. 2016;176(12):1799-1800. doi:10.1001/jamainternmed.2016.6865

Intensive Care Unit Bed Availability and Use of Mechanical Ventilation in Nursing Home Residents With Advanced DementiaWhen We Build It, Why Do They Come?

Abstract Full Text
JAMA Intern Med. 2016;176(12):1816-1817. doi:10.1001/jamainternmed.2016.6415
Editor's Note

The Medicalization of Common Conditions

Abstract Full Text
JAMA Intern Med. 2016;176(12):1863. doi:10.1001/jamainternmed.2016.6210
Review

Economic Evaluation of Quality Improvement Interventions for Bloodstream Infections Related to Central CathetersA Systematic Review

Abstract Full Text
JAMA Intern Med. 2016;176(12):1843-1854. doi:10.1001/jamainternmed.2016.6610

This systematic review of economic evaluations from 113 US hospitals examines the value of quality improvement interventions designed to prevent bloodstream infections related to central catheters.

Evidence to Practice

Update on Percutaneous Coronary Intervention in Stable Coronary Artery Disease

Abstract Full Text
JAMA Intern Med. 2016;176(12):1855-1856. doi:10.1001/jamainternmed.2016.6656

This Evidence to Practice report compares the efficacy, safety, and cost-effectiveness of initial percutaneous coronary intervention with stenting plus guideline-directed medical therapy vs medical therapy alone in patients with stable coronary artery disease.

Teachable Moment

Subclinical Hypothyroidism in Elderly Individuals—Overdiagnosis and Overtreatment?A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2016;176(12):1741-1742. doi:10.1001/jamainternmed.2016.5756

This Teachable Moment describes levothyroxine therapy in elderly patients who might not have subclinical hypothyroidism.

Low Testosterone in Men Should Be a Sign Rather Than a Number to IncreaseA Teachable Moment

Abstract Full Text
JAMA Intern Med. 2016;176(12):1743-1744. doi:10.1001/jamainternmed.2016.5761

This Teachable Moment calls attention to the need to investigate the underlying cause of low testosterone levels or symptoms of hypogonadism.

Antibiotic Treatment for Chronic Lyme Disease—Say No to the DRESS

Abstract Full Text
JAMA Intern Med. 2016;176(12):1745-1746. doi:10.1001/jamainternmed.2016.6229

This Teachable Moment describes the case of a woman who developed DRESS syndrome after unnecessary treatment for “chronic Lyme disease.”

Overdiagnosis of Coronary Artery Disease Detected by Coronary Computed Tomography AngiographyA Teachable Moment

Abstract Full Text
JAMA Intern Med. 2016;176(12):1747-1748. doi:10.1001/jamainternmed.2016.6660

This Teachable Moment presents a case of overdiagnosis and overtreatment of coronary artery disease detected by coronary computed tomography angiography.

Challenges in Clinical Electrocardiography

An Unusually Wide QRS Complex Tachycardia in a Patient With Hemodynamic Instability

Abstract Full Text
JAMA Intern Med. 2016;176(12):1857-1859. doi:10.1001/jamainternmed.2016.6668
Research Letter

Comparison of Physician and Computer Diagnostic Accuracy

Abstract Full Text
JAMA Intern Med. 2016;176(12):1860-1861. doi:10.1001/jamainternmed.2016.6001

This study compares the performance of physicians with computerized symptom checkers in diagnostic accuracy.

Prediabetes Risk in Adult Americans According to a Risk Test

Abstract Full Text
JAMA Intern Med. 2016;176(12):1861-1863. doi:10.1001/jamainternmed.2016.5919

Using data from the 2013-2014 NHANES population, this study provides an estimate of the proportion of nondiabetic adults who would be classified as being at high risk for prediabetes according to a web-based risk test.

Estimating 1-Year Mortality for High-Risk Primary Care Patients Using the “Surprise” Question

Abstract Full Text
JAMA Intern Med. 2016;176(12):1863-1865. doi:10.1001/jamainternmed.2016.5928

This study assesses the potential of the “surprise” question to identify patients who might benefit from palliative care.

Pokémon GO—A New Distraction for Drivers and Pedestrians

Abstract Full Text
JAMA Intern Med. 2016;176(12):1865-1866. doi:10.1001/jamainternmed.2016.6274

This study reports on an assessment of drivers and pedestrians distracted by Pokémon GO.

Clinicians’ Perceptions of Barriers to Avoiding Inappropriate Imaging for Low Back Pain—Knowing Is Not Enough

Abstract Full Text
JAMA Intern Med. 2016;176(12):1866-1868. doi:10.1001/jamainternmed.2016.6364

This study uses survey data to examine why clinicians still order low-value imaging for nonspecific low back pain contrary to the Choosing Wisely campaign recommendations against it.

Association Between Viewing Health Care Price Information and Choice of Health Care Facility

Abstract Full Text
JAMA Intern Med. 2016;176(12):1868-1870. doi:10.1001/jamainternmed.2016.6622

This study uses medical claims data to examine the association of viewing price information with patient choice of health care facility for 8 common procedures.

Frequency of First-line Antibiotic Selection Among US Ambulatory Care Visits for Otitis Media, Sinusitis, and Pharyngitis

Abstract Full Text
JAMA Intern Med. 2016;176(12):1870-1872. doi:10.1001/jamainternmed.2016.6625

This study measures the frequency with which first-line antibiotics are prescribed for otitis media, sinusitis, and pharyngitis.

Low Completion and Disparities in Advance Care Planning Activities Among Older Medicare Beneficiaries

Abstract Full Text
JAMA Intern Med. 2016;176(12):1872-1875. doi:10.1001/jamainternmed.2016.6751

This study examines engagement in advance care planning among older Medicare beneficiaries.

Comment & Response

Differences in Electrocardiographic Findings Between Acute Isolated Right Ventricular Myocardial Infarction and Acute Anterior Myocardial Infarction

Abstract Full Text
JAMA Intern Med. 2016;176(12):1875. doi:10.1001/jamainternmed.2016.6781

Differences in Electrocardiographic Findings Between Acute Isolated Right Ventricular Myocardial Infarction and Acute Anterior Myocardial Infarction

Abstract Full Text
JAMA Intern Med. 2016;176(12):1875-1876. doi:10.1001/jamainternmed.2016.6784

Low-Density Lipoprotein Levels and Risk of Major Cardiovascular Events

Abstract Full Text
JAMA Intern Med. 2016;176(12):1876. doi:10.1001/jamainternmed.2016.6862

Low-Density Lipoprotein Levels and Risk of Major Cardiovascular Events—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(12):1876-1877. doi:10.1001/jamainternmed.2016.6871

Cancer Care Institutions and Advertising

Abstract Full Text
JAMA Intern Med. 2016;176(12):1877. doi:10.1001/jamainternmed.2016.6952

Cancer Care Institutions and Advertising—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(12):1877-1878. doi:10.1001/jamainternmed.2016.6960

Association of Specific Dietary Fats With Mortality

Abstract Full Text
JAMA Intern Med. 2016;176(12):1878. doi:10.1001/jamainternmed.2016.7125

Association of Specific Dietary Fats With Mortality

Abstract Full Text
JAMA Intern Med. 2016;176(12):1878-1879. doi:10.1001/jamainternmed.2016.7131

Association of Specific Dietary Fats With Mortality—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(12):1879-1880. doi:10.1001/jamainternmed.2016.7137

The Complexities of Colorectal Cancer Screening

Abstract Full Text
JAMA Intern Med. 2016;176(12):1880. doi:10.1001/jamainternmed.2016.7134

Important Distinctions Concerning Pharmaceutical Company–Sponsored Meals and Prescribing Patterns

Abstract Full Text
JAMA Intern Med. 2016;176(12):1880-1881. doi:10.1001/jamainternmed.2016.7154

Important Distinctions Concerning Pharmaceutical Company–Sponsored Meals and Prescribing Patterns—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(12):1881. doi:10.1001/jamainternmed.2016.7157

Costs of Inpatient Medications: Do Dispensing and Nursing Fees Lead to Overestimates?

Abstract Full Text
JAMA Intern Med. 2016;176(12):1881-1882. doi:10.1001/jamainternmed.2016.7255

Costs of Inpatient Medications: Do Dispensing and Nursing Fees Lead to Overestimates?—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(12):1882-1883. doi:10.1001/jamainternmed.2016.7258

Importance of Determining Maximal Heart Rate for Providing a Standardized Training Stimulus

Abstract Full Text
JAMA Intern Med. 2016;176(12):1883. doi:10.1001/jamainternmed.2016.7347

Importance of Determining Maximal Heart Rate for Providing a Standardized Training Stimulus—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(12):1883-1884. doi:10.1001/jamainternmed.2016.7350
Correction

Change in Title

Abstract Full Text
JAMA Intern Med. 2016;176(12):1884. doi:10.1001/jamainternmed.2016.7963
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
JAMA Intern Med. 2016;176(12):1738. doi:10.1001/jamainternmed.2015.4919
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