Shreibati and colleagues measure the impact of ultrasonography screening after the SAAAVE Act. In an invited commentary, Sheridan and colleagues further elucidate the topic.
To elucidate patterns of antibiotic prescribing, Zhang and colleagues used Medicare Part D data to examine geographic variation in antibiotic use among older adults in 306 Dartmouth Atlas of Health Care hospital referral regions, 50 states and the District of Columbia, and 4 national regions (South, West, Midwest, and Northeast). See invited commentary by Gonzales et al and letter by Fairlie et al.
Leung and coauthors conducted a cohort study using the American College of Surgeons National Surgical Quality Improvement Program database to determine whether preoperative hyponatremia is a predictor of 30-day perioperative morbidity and mortality. See invited commentary by Vassalotti and DuPreee.
Witt et al determine the incidence of subsequent thrombosis, recurrent gastrointestinal tract bleeding, and death, as well as the time to resumption of warfarin therapy, during 90 days of follow-up. Brotman and Jaffer provide a commentary.
Vickers and coauthors conducted a systematic review to identify RCTs of acupuncture for chronic pain in which allocation concealment was determined unambiguously to be adequate. Individual patient data meta-analyses were conducted using data from 29 of 31 eligible RCTs, with a total of 17 922 patients evaluated. Please also see the Invited Commentary.
Drug shortages present a practical and ethical dilemma to health care providers. Rosoff et al describe a comprehensive and ethically defensible policy to oversee allocation of scarce drugs.
The prolonged process of dying brings special challenges to the physicians who care for these patients. Kissane proposes a typology for the existential challenges of death and dying in modern medicine.
Prasad and colleagues review outcomes effects of current noninvasive testing practices for patients admitted with chest pains to the emergency department.