Hirsch et al performed a comprehensive, systematic analysis of oncology clinical trials, using a triaged ClinicalTrials.gov database. See the invited commentary by Bach.
Flood et al conducted a retrospective cohort study of 818 patients aged 70 years or older hospitalized in either the Acute Care for Elders (ACE) or usual care unit at the University of Alabama at Birmingham in fiscal year 2010. See the invited commentary by Walke and Tinetti.
Hung et al conducted a prospective, matched cohort study of elderly patients admitted because of an acute illness to either the Mobile Acute Care of the Elderly (MACE) service or medicine service of a tertiary hospital. See the invited commentary by Walke and Tinetti.
Davidson and coauthors performed a multicenter randomized controlled trial with 150 patients with elevated depressive symptoms (Beck Depression Inventory score >10) 2 to 6 months after an acute coronary syndrome event. Also see the Invited Commentary by Simon.
Linos et al compare nonmelanoma skin cancer treatments and outcomes in patients with and without limited life expectancy. See Invited Commentary by Wenger.
Puetz et al use a meta-analysis to study the effect of creative arts therapies in patients undergoing cancer treatment. See also the invited commentary by Bradt and Goodill.
Doshi challenges the basic assumptions of influenza vaccination and argues that decisions surrounding influenza vaccines need to include a discussion of related risks and benefits.
Little guidance exists for health care practitioners and institutions on addressing social needs in clinical settings. Gottlieb et al propose a framework for how social determinants interventions can be construed and describe ways to collect data and target interventions.