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August 2017 - January 1908

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January 2014, Vol 174, No. 1, Pages 1-169

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
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JAMA Intern Med. 2014;174(1):1-3. doi:10.1001/jamainternmed.2013.10630
Viewpoint

Screening for Colorectal Cancer in Individuals at Average RiskCurrent Methods and Emerging Issues

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JAMA Intern Med. 2014;174(1):10-11. doi:10.1001/jamainternmed.2013.11499
Perspective

Less Is More

Preoperative Chest X-raysA Teachable Moment

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JAMA Intern Med. 2014;174(1):12. doi:10.1001/jamainternmed.2013.10531

“Saving” Bonnie

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JAMA Intern Med. 2014;174(1):13-14. doi:10.1001/jamainternmed.2013.12104
Editorial

Atrial Fibrillation Begets Myocardial Infarction

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JAMA Intern Med. 2014;174(1):5-7. doi:10.1001/jamainternmed.2013.11392

Less Is More

Too Much Medicine Happens Too OftenThe Teachable Moment and a Call for Manuscripts From Clinical Trainees

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JAMA Intern Med. 2014;174(1):8-9. doi:10.1001/jamainternmed.2013.9967
Original Investigation

Myocardial Infarction and Ischemic Heart Disease in Overweight and Obesity With and Without Metabolic Syndrome

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JAMA Intern Med. 2014;174(1):15-22. doi:10.1001/jamainternmed.2013.10522

Thomsen and Nordestgaard test the hypothesis that overweight and obesity with and without metabolic syndrome are associated with increased risk of myocardial infarction and ischemic heart disease. Jackson provides an Invited Commentary.

Lower Risk of Cardiovascular Events in Postmenopausal Women Taking Oral Estradiol Compared With Oral Conjugated Equine Estrogens

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JAMA Intern Med. 2014;174(1):25-34. doi:10.1001/jamainternmed.2013.11074

Smith et al compare the relative clinical cardiovascular safety of 2 commonly used oral estrogen drugs—conjugated equine estrogens and estradiol. Their case-control study compares cardiovascular event risk among 384 postmenopausal women aged 30 to 79 years using oral hormone therapy. Incident venous thrombosis was the primary clinical outcome.

Falling Threshold for Treatment of Borderline Elevated Thyrotropin Levels—Balancing Benefits and RisksEvidence From a Large Community-Based Study

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JAMA Intern Med. 2014;174(1):32-39. doi:10.1001/jamainternmed.2013.11312

To define trends in thyrotropin levels at the initiation of levothyroxine therapy and the risk of developing a suppressed thyrotropin level after treatment, Taylor et al performed a retrospective cohort study using data from the UK Clinical Practice Research Datalink. They assessed the odds of initiation of therapy at thyrotropin levels of 10.0 mIU/L or less.

An Education Program for Risk Factor Management After an Acute Coronary SyndromeA Randomized Clinical Trial

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JAMA Intern Med. 2014;174(1):40-48. doi:10.1001/jamainternmed.2013.11342

Cohen et al determined whether a nurse-led or dietician-led cardiovascular risk factor education program would improve risk factor reduction over the long term after an acute coronary syndrome. Patients underwent an education program in a House of Education or were treated according to physicians’ standard of care. See the Invited Commentary by Fihn.

A 2-Hour Diagnostic Protocol for Possible Cardiac Chest Pain in the Emergency DepartmentA Randomized Clinical Trial

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JAMA Intern Med. 2014;174(1):51-58. doi:10.1001/jamainternmed.2013.11362

Than and coauthors compared the effectiveness of a rapid diagnostic pathway with a standard-care diagnostic pathway for the assessment of patients with possible cardiac chest pain in a usual clinical practice setting. See also the Invited Commentary by Rahko.

Compensation of Chief Executive Officers at Nonprofit US Hospitals

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JAMA Intern Med. 2014;174(1):61-67. doi:10.1001/jamainternmed.2013.11537

Joynt et al examine CEO compensation at private nonprofit hospitals and examine its relationship with quality metrics. Invited commentary provided by Browner.

Gabapentin Treatment for Alcohol DependenceA Randomized Clinical Trial

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JAMA Intern Med. 2014;174(1):70-77. doi:10.1001/jamainternmed.2013.11950

Mason and coauthors determine if gabapentin increases rates of sustained abstinence and no heavy drinking and decreases alcohol-related insomnia, dysphoria, and craving, in a dose-dependent manner. See the Invited Commentary by Nunes.

Features and Outcomes of Patients Who Underwent Cardiac Device Deactivation

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JAMA Intern Med. 2014;174(1):80-85. doi:10.1001/jamainternmed.2013.11564

Buchhalter and colleagues describe features and outcomes of patients who underwent cardiovascular implantable electronic device deactivation. Also see the Invited Commentary by Matlock and Mandrola.

Development Times, Clinical Testing, Postmarket Follow-up, and Safety Risks for the New Drugs Approved by the US Food and Drug AdministrationThe Class of 2008

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JAMA Intern Med. 2014;174(1):90-95. doi:10.1001/jamainternmed.2013.11813

To inform the debate about appropriate standards, Moore and Furberg studied the development times, clinical testing, postmarket follow-up, and safety risks for the new drugs approved by the US FDA in 2008. Carpenter provides an Invited Commentary.

Obesity and Late-Age Survival Without Major Disease or Disability in Older Women

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JAMA Intern Med. 2014;174(1):98-106. doi:10.1001/jamainternmed.2013.12051

Rillamas-Sun and colleagues investigate whether higher baseline body mass index and waist circumference affect women’s survival to age 85 years without major chronic disease (coronary disease, stroke, cancer, diabetes mellitus, or hip fracture) and mobility disability.

Atrial Fibrillation and the Risk of Myocardial Infarction

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JAMA Intern Med. 2014;174(1):107-114. doi:10.1001/jamainternmed.2013.11912

Soliman and colleagues examine the risk of incident myocardial infarction (MI) associated with atrial fibrillation (AF). In a related editorial, Dukes and Marcus further explore the association between MI and AF.

Rapid Increase in Breast Magnetic Resonance Imaging UseTrends From 2000 to 2011

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JAMA Intern Med. 2014;174(1):114-121. doi:10.1001/jamainternmed.2013.11958

Stout et al describe breast magnetic resonance imaging trends and indications in a community setting.

Patterns of Breast Magnetic Resonance Imaging Use in Community Practice

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JAMA Intern Med. 2014;174(1):125-132. doi:10.1001/jamainternmed.2013.11963

Wernli et al describe patterns of breast magnetic resonance imaging use in US community practice during the period 2005 through 2009.

Invited Commentary

Maintaining a Healthy Body Weight Is Paramount

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JAMA Intern Med. 2014;174(1):23-24. doi:10.1001/jamainternmed.2013.8298

Bending the Curve on Cardiovascular Risk

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JAMA Intern Med. 2014;174(1):48-50. doi:10.1001/jamainternmed.2013.9498

Rapid Evaluation of Chest Pain in the Emergency Department

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JAMA Intern Med. 2014;174(1):59-60. doi:10.1001/jamainternmed.2013.9978

Do Hospitals Really Reward Glitz but Not Quality?

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JAMA Intern Med. 2014;174(1):68-69. doi:10.1001/jamainternmed.2013.7669

GabapentinA New Addition to the Armamentarium for Alcohol Dependence?

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JAMA Intern Med. 2014;174(1):78-79. doi:10.1001/jamainternmed.2013.11973

The Antidote for Unprepared PatientsA Caring Clinician

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JAMA Intern Med. 2014;174(1):86-87. doi:10.1001/jamainternmed.2013.9196

Deathbed ShockCauses and Cures

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JAMA Intern Med. 2014;174(1):88-89. doi:10.1001/jamainternmed.2013.11125

Can Expedited FDA Drug Approval Without Expedited Follow-up Be Trusted?

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JAMA Intern Med. 2014;174(1):95-97. doi:10.1001/jamainternmed.2013.9202

Patterns of Breast Magnetic Resonance Imaging UseAn Opportunity for Data-Driven Resource Allocation

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JAMA Intern Med. 2014;174(1):122-124. doi:10.1001/jamainternmed.2013.10502

Examine Critical Access Hospital Payment Policies Within the Context of Integrated Systems

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JAMA Intern Med. 2014;174(1):144-145. doi:10.1001/jamainternmed.2013.11469

Ischemic Heart Disease and Breast Cancer RadiotherapyThe Way Forward

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JAMA Intern Med. 2014;174(1):160-161. doi:10.1001/jamainternmed.2013.9131
Editor's Note

Palliative Care = Hope

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JAMA Intern Med. 2014;174(1):14. doi:10.1001/jamainternmed.2013.9309

The Centers for Medicare & Medicaid Services and Amyloid-β Positron Emission Tomography for Alzheimer Disease

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JAMA Intern Med. 2014;174(1):135. doi:10.1001/jamainternmed.2013.11705

Choosing Wisely, and Soon

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JAMA Intern Med. 2014;174(1):140. doi:10.1001/jamainternmed.2013.11672

Approaches to Increase Physical Activity

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JAMA Intern Med. 2014;174(1):149. doi:10.1001/jamainternmed.2013.11487

Multiple Data Sources, the Best Way to Gather Safety Information About Medications

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JAMA Intern Med. 2014;174(1):151. doi:10.1001/jamainternmed.2013.11488
Evidence to Practice

Amyloid-β Positron Emission Tomography in the Diagnostic Evaluation of Alzheimer DiseaseSummary of Primary Findings and Conclusions

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JAMA Intern Med. 2014;174(1):133-134. doi:10.1001/jamainternmed.2013.11711

The Institute of Medicine Report Sodium Intake in Populations: Assessment of EvidenceSummary of Primary Findings and Implications for Clinicians

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JAMA Intern Med. 2014;174(1):136-137. doi:10.1001/jamainternmed.2013.11818
Research Letter

Antibiotic Prescribing to Adults With Sore Throat in the United States, 1997-2010

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JAMA Intern Med. 2014;174(1):138-140. doi:10.1001/jamainternmed.2013.11673

Health Care Reform

Cost-Effectiveness Decision Making and US Public Opinion

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JAMA Intern Med. 2014;174(1):141-143. doi:10.1001/jamainternmed.2013.11332

Health Care Reform

Critical Access Hospitals and Cost Shifting

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JAMA Intern Med. 2014;174(1):143-144. doi:10.1001/jamainternmed.2013.11901

Circaseptan (Weekly) Rhythms in Smoking Cessation Considerations

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JAMA Intern Med. 2014;174(1):146-148. doi:10.1001/jamainternmed.2013.11933

Physical Activity Profiles of Overweight and Obese Women in Rural Georgia

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JAMA Intern Med. 2014;174(1):148-149. doi:10.1001/jamainternmed.2013.11571

A Comparison of Results of the US Food and Drug Administration’s Mini-Sentinel Program With Randomized Clinical TrialsThe Case of Gastrointestinal Tract Bleeding With Dabigatran

Abstract Full Text
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JAMA Intern Med. 2014;174(1):150-151. doi:10.1001/jamainternmed.2013.12217

Digitalis Use in Contemporary Clinical PracticeRefitting the Foxglove

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JAMA Intern Med. 2014;174(1):151-154. doi:10.1001/jamainternmed.2013.10432

Contemporary Data About Hospital Strategies to Reduce Unplanned ReadmissionsWhat Has Changed?

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JAMA Intern Med. 2014;174(1):154-156. doi:10.1001/jamainternmed.2013.11574

Trends in Emergency Department Visits for Ambulatory Care Sensitive Conditions by Elderly Nursing Home Residents, 2001 to 2010

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JAMA Intern Med. 2014;174(1):156-158. doi:10.1001/jamainternmed.2013.11821

Risk and Risk Reduction of Major Coronary Events Associated With Contemporary Breast Radiotherapy

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JAMA Intern Med. 2014;174(1):158-160. doi:10.1001/jamainternmed.2013.11790
Comment & Response

Considerations for Attending Rounds

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JAMA Intern Med. 2014;174(1):161. doi:10.1001/jamainternmed.2013.11100

Considerations for Attending Rounds

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JAMA Intern Med. 2014;174(1):161-162. doi:10.1001/jamainternmed.2013.11122

Considerations for Attending Rounds—Reply

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JAMA Intern Med. 2014;174(1):162. doi:10.1001/jamainternmed.2013.11085

Sodium and Fluid RestrictionThe Impact of Quality of Data and Reporting on the Conclusion

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JAMA Intern Med. 2014;174(1):162-163. doi:10.1001/jamainternmed.2013.11103

Sodium and Fluid Restriction—Reply

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JAMA Intern Med. 2014;174(1):163-164. doi:10.1001/jamainternmed.2013.11088

Why I Will Continue to Screen Prostate-Specific Antigen for Myself and Other Appropriate Men—Reply

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JAMA Intern Med. 2014;174(1):164. doi:10.1001/jamainternmed.2013.11095

Why I Will Continue to Screen Prostate-Specific Antigen for Myself and Other Appropriate Men

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JAMA Intern Med. 2014;174(1):164. doi:10.1001/jamainternmed.2013.11106

Further Thoughts on Why There Are Good Data Supporting the Inferior Vena Cava Filter

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JAMA Intern Med. 2014;174(1):164-165. doi:10.1001/jamainternmed.2013.13176

Exercise, Cardiac Rehabilitation, and Post–Acute Coronary Syndrome Depression

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JAMA Intern Med. 2014;174(1):165-166. doi:10.1001/jamainternmed.2013.11112

Exercise, Cardiac Rehabilitation, and Post–Acute Coronary Syndrome Depression—Reply

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JAMA Intern Med. 2014;174(1):166-167. doi:10.1001/jamainternmed.2013.11097

Phenytoin Toxicity Unlikely to Result in Arrhythmias—Reply

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JAMA Intern Med. 2014;174(1):167-168. doi:10.1001/jamainternmed.2013.11168

Phenytoin Toxicity Unlikely to Result in Arrhythmias

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JAMA Intern Med. 2014;174(1):167. doi:10.1001/jamainternmed.2013.11177

Lack of Adjustment for Body Mass Index

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JAMA Intern Med. 2014;174(1):168-169. doi:10.1001/jamainternmed.2013.11171

Lack of Adjustment for Body Mass Index—Reply

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JAMA Intern Med. 2014;174(1):169. doi:10.1001/jamainternmed.2013.11169
Correction

Incorrect Axis Label in Figure

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JAMA Intern Med. 2014;174(1):169. doi:10.1001/jamainternmed.2013.13462
JAMA Internal Medicine Masthead

JAMA Internal Medicine

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JAMA Intern Med. 2014;174(1):4. doi:10.1001/jamainternmed.2013.10631
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