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May 2017 - January 1908

Decade

Year

Issue

December 2014, Vol 174, No. 12, Pages 1881-2037

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):1881-1883. doi:10.1001/jamainternmed.2013.10686
Viewpoint

The Strange Allure of State “Right-to-Try” Laws

Abstract Full Text
JAMA Intern Med. 2014;174(12):1885-1886. doi:10.1001/jamainternmed.2014.5767

State “right-to-try” laws that purport to allow patients to be treated with unapproved drugs or devices seem likely to be futile.

Health Care Reform

The Withdrawal of Drugs for Commercial ReasonsThe Incomplete Story of Tositumomab

Abstract Full Text
JAMA Intern Med. 2014;174(12):1887-1888. doi:10.1001/jamainternmed.2014.5756

This Viewpoint describe the case of the commercial withdrawal of tositumomab as a cautionary tale of the weaknesses in our current drug-approval system.

Perspective

Statin-Related Cognitive Impairment in the Real WorldYou’ll Live Longer, but You Might Not Like It

Abstract Full Text
JAMA Intern Med. 2014;174(12):1889. doi:10.1001/jamainternmed.2014.5376

Less Is More

Acute Renal Failure Following Treatment of a Common Culture ContaminantA Teachable Moment

Abstract Full Text
JAMA Intern Med. 2014;174(12):1890-1891. doi:10.1001/jamainternmed.2014.5281

Less Is More

In-Hospital Delirium While Awaiting Temporal Artery BiopsyA Teachable Moment

Abstract Full Text
JAMA Intern Med. 2014;174(12):1891-1892. doi:10.1001/jamainternmed.2014.5310

Less Is More

Doubts About Treating Hypogonadism Due to Long-term Opioid Use With Testosterone TherapyA Teachable Moment

Abstract Full Text
JAMA Intern Med. 2014;174(12):1892-1893. doi:10.1001/jamainternmed.2014.5299
Original Investigation

β-Lactam Monotherapy vs β-Lactam–Macrolide Combination Treatment in Moderately Severe Community-Acquired PneumoniaA Randomized Noninferiority Trial

Abstract Full Text
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JAMA Intern Med. 2014;174(12):1894-1901. doi:10.1001/jamainternmed.2014.4887

This open-label, multicenter, noninferiority, randomized trial reports that β-lactam monotherapy delays clinical stability for patients with pneumonia. See also the Invited Commentary by Fine.

Attitudes of Hospital Leaders Toward Publicly Reported Measures of Health Care Quality

Abstract Full Text
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JAMA Intern Med. 2014;174(12):1904-1911. doi:10.1001/jamainternmed.2014.5161

This survey study revealed that the local planning and improvement efforts of hospital leaders are strongly influenced by health care quality measures.

Use and Prescription of Antibiotics in Primary Health Care Settings in China

Abstract Full Text
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JAMA Intern Med. 2014;174(12):1914-1920. doi:10.1001/jamainternmed.2014.5214

Wang et al identify current patterns of antibiotic use and explore the reasons for inappropriate prescription in primary health care settings in China.

Estimation of Cigarette Smoking–Attributable Morbidity in the United States

Abstract Full Text
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JAMA Intern Med. 2014;174(12):1922-1928. doi:10.1001/jamainternmed.2014.5219

This quantitative assessment estimates that US adults have approximately 14 million major medical conditions that are attributable to smoking. See also the Invited Commentary by Schroeder.

Reports of Pathological Gambling, Hypersexuality, and Compulsive Shopping Associated With Dopamine Receptor Agonist Drugs

Abstract Full Text
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JAMA Intern Med. 2014;174(12):1930-1933. doi:10.1001/jamainternmed.2014.5262

This disproportionality analysis demonstrates that dopamine receptor agonists can cause impulse control disorders. See also the Invited Commentaries by Weiss and Pontone and Gagne.

Clinical Evidence Supporting Pharmacogenomic Biomarker Testing Provided in US Food and Drug Administration Drug Labels

Abstract Full Text
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JAMA Intern Med. 2014;174(12):1938-1944. doi:10.1001/jamainternmed.2014.5266

This study found that few drug labels contained or referenced convincing evidence of clinical utility of biomarker testing, whereas many made recommendations based on biomarker test results. See also the Invited Commentary by Burke.

Primary Care–Based Buprenorphine Taper vs Maintenance Therapy for Prescription Opioid DependenceA Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2014;174(12):1947-1954. doi:10.1001/jamainternmed.2014.5302

This randomized clinical trial reports that buprenorphine taper is less efficacious than ongoing maintenance treatment in patients dependent on prescription opioids in primary care.

Less Is More

Initial Choice of Oral Glucose-Lowering Medication for Diabetes MellitusA Patient-Centered Comparative Effectiveness Study

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):1955-1962. doi:10.1001/jamainternmed.2014.5294

This retrospective cohort study found that diabetes treatment with metformin reduced subsequent treatment intensification, without differences in rates of adverse clinical events. See also the Invited Commentary by Segal and Maruthur.

Further Insight Into the Cardiovascular Risk CalculatorThe Roles of Statins, Revascularizations, and Underascertainment in the Women’s Health Study

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2014;174(12):1964-1971. doi:10.1001/jamainternmed.2014.5336

The Women’s Health Study is a nationwide cohort of US women free of cardiovascular disease, cancer, or other major illness at baseline from 1992 to 1995. A total of 27 542 women aged 45 to 79 years with complete ascertainment of plasma lipids and other risk factors were followed for a median of 10 years.

Association of Opioid Agonist Therapy With Lower Incidence of Hepatitis C Virus Infection in Young Adult Injection Drug Users

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):1974-1981. doi:10.1001/jamainternmed.2014.5416

This observational cohort study suggests that maintenance treatment with methadone or buprenorphine for opioid use disorders may be an important strategy to prevent the spread of hepatitis C virus (HCV) infection among young injection drug users.

Outcomes Associated With Invasive and Noninvasive Ventilation Among Patients Hospitalized With Exacerbations of Chronic Obstructive Pulmonary Disease

Abstract Full Text
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JAMA Intern Med. 2014;174(12):1982-1993. doi:10.1001/jamainternmed.2014.5430

In a large retrospective cohort study, patients with COPD treated with noninvasive ventilation at the time of hospitalization had lower inpatient mortality, shorter length of stay, and lower costs compared with those treated with invasive mechanical ventilation .

Invited Commentary

The Debate on Antibiotic Therapy for Patients Hospitalized for PneumoniaWhere Should We Go From Here?

Abstract Full Text
JAMA Intern Med. 2014;174(12):1901-1903. doi:10.1001/jamainternmed.2014.3996

Virtual QualityThe Failure of Public Reporting and Pay-for-Performance Programs

Abstract Full Text
JAMA Intern Med. 2014;174(12):1912-1913. doi:10.1001/jamainternmed.2014.3403

Antibiotic MisuseA Global Crisis

Abstract Full Text
JAMA Intern Med. 2014;174(12):1920-1921. doi:10.1001/jamainternmed.2014.3289

Even More Illness Caused by Smoking Than Previously Estimated

Abstract Full Text
JAMA Intern Med. 2014;174(12):1928-1929. doi:10.1001/jamainternmed.2014.4297

Finding Meaningful Patterns in Adverse Drug Event Reports

Abstract Full Text
JAMA Intern Med. 2014;174(12):1934-1935. doi:10.1001/jamainternmed.2014.3270

Dopamine Receptor Agonist Drugs and Impulse Control Disorders

Abstract Full Text
JAMA Intern Med. 2014;174(12):1935-1937. doi:10.1001/jamainternmed.2014.4097

A Call for Accurate Pharmacogenetic LabelingTelling It Like It Is

Abstract Full Text
JAMA Intern Med. 2014;174(12):1945-1946. doi:10.1001/jamainternmed.2014.3276

Initial Therapy for Diabetes Mellitus

Abstract Full Text
JAMA Intern Med. 2014;174(12):1962-1963. doi:10.1001/jamainternmed.2014.4296

Prevention GuidelinesBad Process, Bad Outcome

Abstract Full Text
JAMA Intern Med. 2014;174(12):1972-1973. doi:10.1001/jamainternmed.2014.3278

Shared Savings, Shared Decisions, and Incentives for High-Value Medical Care

Abstract Full Text
JAMA Intern Med. 2014;174(12):2014-2015. doi:10.1001/jamainternmed.2014.2525
Editor's Note

Lung Cancer Screening With Low-Dose Computed Tomography for Medicare Beneficiaries

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):2023. doi:10.1001/jamainternmed.2014.5629
Special Communication

Communication About Serious Illness Care GoalsA Review and Synthesis of Best Practices

Abstract Full Text
has active quiz
JAMA Intern Med. 2014;174(12):1994-2003. doi:10.1001/jamainternmed.2014.5271

This Special Communication reviews the evidence and describes best practices in conversations about serious illness care goals, concluding that such communication is an intervention that should be systematically integrated into our clinical care structures and processes.

Less Is More

The Case Against Identifying Carotid Stenosis in Asymptomatic Patients

Abstract Full Text
JAMA Intern Med. 2014;174(12):2004-2008. doi:10.1001/jamainternmed.2014.4920

This special communication concludes that there is currently no role for carotid imaging in patients without a history of carotid-territory stroke or transient ischemic attack.

Lowering Medical Costs Through the Sharing of Savings by Physicians and PatientsInclusive Shared Savings

Abstract Full Text
JAMA Intern Med. 2014;174(12):2009-2013. doi:10.1001/jamainternmed.2014.5367

This Special Communication proposes inclusive shared savings, an alternative method to control medical costs that retains physicians’ incentives for providing lower-cost but otherwise equivalent interventions through the shared savings model and extends the shared savings to patients.

Health Care Reform

The Importance of Lung Cancer Screening With Low-Dose Computed Tomography for Medicare Beneficiaries

Abstract Full Text
JAMA Intern Med. 2014;174(12):2016-2018. doi:10.1001/jamainternmed.2014.5623

This Special Communication argues for low-dose computed tomography screening for lung cancer in Medicare beneficiaries.

Low-Dose Computed Tomography Screening for Lung CancerHow Strong Is the Evidence?

Abstract Full Text
JAMA Intern Med. 2014;174(12):2019-2022. doi:10.1001/jamainternmed.2014.5626

This Special Communication argues that low-dose CT screening for lung cancer in Medicare recipients should not be implemented until more and better evidence has been collected that the benefits outweigh the risks.

Challenges in Clinical Electrocardiography

The Importance of the Ladder Diagram in the Evaluation of TachyarrhythmiaJumping to Conclusions

Abstract Full Text
JAMA Intern Med. 2014;174(12):2024-2026. doi:10.1001/jamainternmed.2014.5231

A Patient With Systolic Dysfunction and an Alternating Axis

Abstract Full Text
JAMA Intern Med. 2014;174(12):2027-2028. doi:10.1001/jamainternmed.2014.5452
Research Letter

Time of Day and the Decision to Prescribe Antibiotics

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):2029-2031. doi:10.1001/jamainternmed.2014.5225

Cigarette Purchases at Pharmacies by Patients at High Risk of Smoking-Related Illness

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):2031-2032. doi:10.1001/jamainternmed.2014.5307

Less Is More

Computer-Aided Detection in MammographyDownstream Effect on Diagnostic Testing, Ductal Carcinoma In Situ Treatment, and Costs

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):2032-2034. doi:10.1001/jamainternmed.2014.5410

Presentation of Prescription and Nonprescription Opioid Overdoses to US Emergency Departments

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):2034-2037. doi:10.1001/jamainternmed.2014.5413
Correction

Error in Byline

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):2037. doi:10.1001/jamainternmed.2014.5989

Error in Text

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):2037. doi:10.1001/jamainternmed.2014.6040

Error in Affiliations

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):2037. doi:10.1001/jamainternmed.2014.6213
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
free access
JAMA Intern Med. 2014;174(12):1884. doi:10.1001/jamainternmed.2013.10687
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