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July 1, 2014, Vol 174, No. 7, Pages 1017-1205

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1017-1018. doi:10.1001/jamainternmed.2013.10660
Viewpoint

Bringing High-Value Care to the Inpatient Teaching Service

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JAMA Intern Med. 2014;174(7):1021-1022. doi:10.1001/jamainternmed.2014.2012

The Role of Testing for BRCA1 and BRCA2 Mutations in Cancer Prevention

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JAMA Intern Med. 2014;174(7):1023-1024. doi:10.1001/jamainternmed.2014.1322

Expanding the Roles of Medical AssistantsWho Does What in Primary Care?

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JAMA Intern Med. 2014;174(7):1025-1026. doi:10.1001/jamainternmed.2014.1319

Choosing a Screening Method for Cervical CancerPapanicolaou Testing Alone or With Human Papillomavirus Testing

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JAMA Intern Med. 2014;174(7):1027-1028. doi:10.1001/jamainternmed.2014.1368

Can the New Cervical Cancer Screening and Management Guidelines Be Simplified?

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JAMA Intern Med. 2014;174(7):1029-1030. doi:10.1001/jamainternmed.2014.576
Perspective

Allopurinol Overuse in Asymptomatic HyperuricemiaA Teachable Moment

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JAMA Intern Med. 2014;174(7):1031-1032. doi:10.1001/jamainternmed.2014.1427

Approach to Overuse of Herbal and Dietary SupplementsA Teachable Moment

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JAMA Intern Med. 2014;174(7):1033-1034. doi:10.1001/jamainternmed.2014.1879

An Adverse Reaction to a Medication Given to Treat an Adverse ReactionA Teachable Moment

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JAMA Intern Med. 2014;174(7):1035-1036. doi:10.1001/jamainternmed.2014.1605

The Diagnostic and Healing Qualities of StoryGoals of Care

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JAMA Intern Med. 2014;174(7):1037. doi:10.1001/jamainternmed.2014.1800
Original Investigation

Different Time Trends of Caloric and Fat Intake Between Statin Users and Nonusers Among US AdultsGluttony in the Time of Statins?

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JAMA Intern Med. 2014;174(7):1038-1045. doi:10.1001/jamainternmed.2014.1927

Sugiyama and colleagues examine the difference in the temporal trends of caloric and fat intake between statin users and nonusers among US adults.

Physical Activity and Sedentary Behaviors Associated With Risk of Progression From Gestational Diabetes Mellitus to Type 2 Diabetes MellitusA Prospective Cohort Study

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1047-1055. doi:10.1001/jamainternmed.2014.1795

Bao et al examine the role of physical activity and television watching and other sedentary behaviors, and changes in these behaviors in the progression from gestational diabetes mellitus to type 2 diabetes mellitus. Hedderson and Ferrara provide an Invited Commentary.

Low-Dose Estradiol and the Serotonin-Norepinephrine Reuptake Inhibitor Venlafaxine for Vasomotor SymptomsA Randomized Clinical Trial

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JAMA Intern Med. 2014;174(7):1058-1066. doi:10.1001/jamainternmed.2014.1891

Joffe et al determine the efficacy and tolerability of low-dose oral 17β-estradiol and low-dose venlafaxine extended release in alleviating vasomotor symptoms. The primary outcome was the mean daily frequency of vasomotor symptoms after 8 weeks of treatment among 339 perimenopausal and postmenopausal women with at least 2 bothersome symptoms per day.

Measuring Low-Value Care in Medicare

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1067-1076. doi:10.1001/jamainternmed.2014.1541

Schwartz et al develop claims-based measures of low-value services, examine service use (and associated spending) detected by these measures in Medicare, and determine whether patterns of use are related across different types of low-value services. See also the editor’s note by Katz et al.

Resveratrol Levels and All-Cause Mortality in Older Community-Dwelling Adults

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JAMA Intern Med. 2014;174(7):1077-1084. doi:10.1001/jamainternmed.2014.1582

Semba and colleagues set out to determine whether resveratrol levels achieved with diet are associated with inflammation, cancer, cardiovascular disease, and mortality in humans.

Stability of End-of-Life PreferencesA Systematic Review of the Evidence

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JAMA Intern Med. 2014;174(7):1085-1092. doi:10.1001/jamainternmed.2014.1183

Auriemma and coauthors systematically evaluate the evidence on the stability of end-of-life preferences over time and with changes in health status.

Preventing 30-Day Hospital ReadmissionsA Systematic Review and Meta-analysis of Randomized Trials

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JAMA Intern Med. 2014;174(7):1095-1107. doi:10.1001/jamainternmed.2014.1608

Leppin et al synthesize the evidence of the efficacy of interventions to reduce early hospital readmissions and identify intervention features—including their impact on treatment burden and on patients’ capacity to enact postdischarge self-care—that might explain their varying effects.

Diagnostic Performance of Random Urine Samples Using Albumin Concentration vs Ratio of Albumin to Creatinine for Microalbuminuria Screening in Patients With Diabetes MellitusA Systematic Review and Meta-analysis

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1108-1115. doi:10.1001/jamainternmed.2014.1363

Wu et al compare the diagnostic performance of the UAC vs the ACR in random urine samples for microalbuminuria screening among patients with DM. A literature search identified clinical studies assessing the UAC or the ACR using a urinary albumin excretion rate of 30 to 300 mg/d in 24-hour timed urine collections as the criterion standard.

National Trends in US Hospital Admissions for Hyperglycemia and Hypoglycemia Among Medicare Beneficiaries, 1999 to 2011

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1116-1124. doi:10.1001/jamainternmed.2014.1824

Lipska and coauthors characterize changes in hyperglycemia and hypoglycemia hospitalization rates and subsequent mortality and readmission rates among older adults in the United States over a 12-year period and compare these results according to age, sex, and race.

Fracture Prediction After Discontinuation of 4 to 5 Years of Alendronate TherapyThe FLEX Study

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JAMA Intern Med. 2014;174(7):1126-1134. doi:10.1001/jamainternmed.2014.1232

Bauer et al test methods of predicting fracture risk among women who have discontinued alendronate therapy after 4 to 5 years of treatment.

Invasive Group A Streptococcus Infections Associated With Liposuction Surgery at Outpatient Facilities Not Subject to State or Federal Regulation

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1136-1142. doi:10.1001/jamainternmed.2014.1875

Beaudoin et al describe an outbreak of severe group A Streptococcus infections among persons undergoing tumescent liposuction between July 1 and September 14, 2012, at 2 outpatient cosmetic surgery facilities (one in Maryland and the other in Pennsylvania) not subject to state or federal regulation. See the invited commentary by Morgan and Harris.

A Comparison of Live Counseling With a Web-Based Lifestyle and Medication Intervention to Reduce Coronary Heart Disease RiskA Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1144-1157. doi:10.1001/jamainternmed.2014.1984

Keyserling and colleagues assess the effectiveness, acceptability, and cost-effectiveness of a combined lifestyle and medication intervention to reduce coronary heart disease risk offered in counselor-based and web-based formats. In their related Invited Commentary, Moin and Mangione expand on the topic.

Impact of an Intensive Care Unit Telemedicine Program on Patient Outcomes in an Integrated Health Care System

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1160-1167. doi:10.1001/jamainternmed.2014.1503

Nassar and colleagues examine the impact of ICU TM on mortality rates and length of stay in an integrated health care system. See also the invited commentary by Wilcox and Wiener-Kronish.

Invited Commentary

A Call to Increase Physical Activity Among Women of Reproductive AgeIs It Possible?

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JAMA Intern Med. 2014;174(7):1056-1057. doi:10.1001/jamainternmed.2014.709

What Should Be the Goal of Advance Care Planning?

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JAMA Intern Med. 2014;174(7):1093-1094. doi:10.1001/jamainternmed.2014.1887

Bone Density and Bone Turnover Marker Monitoring After Discontinuation of Alendronate TherapyAn Evidence-Based Decision to Do Less

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JAMA Intern Med. 2014;174(7):1134-1135. doi:10.1001/jamainternmed.2014.162

The Gap in Patient Protection for Outpatient Cosmetic Surgery

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JAMA Intern Med. 2014;174(7):1142-1143. doi:10.1001/jamainternmed.2014.441

Live vs Electronically Delivered Weight-Loss InterventionsPaying for Feasible Interventions

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JAMA Intern Med. 2014;174(7):1157-1159. doi:10.1001/jamainternmed.2014.414

Telemedicine in the Intensive Care UnitEffect of a Remote Intensivist on Outcomes

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JAMA Intern Med. 2014;174(7):1167-1169. doi:10.1001/jamainternmed.2014.289
Editor's Note

Statins and Weight Gain

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JAMA Intern Med. 2014;174(7):1046. doi:10.1001/jamainternmed.2014.1994

Developing Methods for Less Is More

Abstract Full Text
JAMA Intern Med. 2014;174(7):1076. doi:10.1001/jamainternmed.2014.1101

Hospital Admissions for Hypoglycemia Now Exceed Those for Hyperglycemia in Medicare Beneficiaries

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JAMA Intern Med. 2014;174(7):1125. doi:10.1001/jamainternmed.2014.2192

The High Price of the New Hepatitis C Virus Drugs

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JAMA Intern Med. 2014;174(7):1172. doi:10.1001/jamainternmed.2014.2135
Special Communication

Descriptions and Interpretations of the ACCORD-Lipid Trial in the News and Biomedical LiteratureA Cross-Sectional Analysis

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JAMA Intern Med. 2014;174(7):1176-1182. doi:10.1001/jamainternmed.2014.1371

Downing et al review news stories and biomedical literature discussing the Action to Control Cardiovascular Risk in Diabetes (ACCORD-Lipid) trial published within 15 months after results of the trial were presented.

A Guide to Reading Health Care News Stories

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JAMA Intern Med. 2014;174(7):1183-1186. doi:10.1001/jamainternmed.2014.1359

Schwitzer provides a guide to reading health care news stories to help physicians and the public better understand the strengths and weaknesses of news media coverage of medical and health topics

Evidence to Practice

The Comparative Clinical Effectiveness and Value of Simeprevir and Sofosbuvir for Chronic Hepatitis C Virus Infection

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JAMA Intern Med. 2014;174(7):1170-1171. doi:10.1001/jamainternmed.2014.2151
Challenges in Clinical Electrocardiography

A Rare Cause of Chest Pain and Ventricular Fibrillation

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JAMA Intern Med. 2014;174(7):1173-1175. doi:10.1001/jamainternmed.2014.1809
Research Letter

Decade-Long Trends in Mortality Among Patients With and Without Diabetes Mellitus at a Major Academic Medical Center

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1187-1188. doi:10.1001/jamainternmed.2014.1803

Functional Impairment and Internet Use Among Older AdultsImplications for Meaningful Use of Patient Portals

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1188-1190. doi:10.1001/jamainternmed.2014.1864

The Effect of a Physician Partner Program on Physician Efficiency and Patient Satisfaction

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JAMA Intern Med. 2014;174(7):1190-1193. doi:10.1001/jamainternmed.2014.1315
Comment & Response

Meditation Intervention Reviews

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JAMA Intern Med. 2014;174(7):1193. doi:10.1001/jamainternmed.2014.1419

Meditation Intervention Reviews

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JAMA Intern Med. 2014;174(7):1193-1194. doi:10.1001/jamainternmed.2014.1422

Meditation Intervention Reviews

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JAMA Intern Med. 2014;174(7):1194-1195. doi:10.1001/jamainternmed.2014.1924

Meditation Intervention Reviews—Reply

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JAMA Intern Med. 2014;174(7):1195. doi:10.1001/jamainternmed.2014.1393

Assessing the Clinical Impact of Appropriate Echocardiograms

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JAMA Intern Med. 2014;174(7):1195-1196. doi:10.1001/jamainternmed.2014.1440

Assessing the Clinical Impact of Appropriate Echocardiograms—Reply

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JAMA Intern Med. 2014;174(7):1196-1197. doi:10.1001/jamainternmed.2014.1437

Estimating Overdiagnosis in Lung Cancer Screening

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JAMA Intern Med. 2014;174(7):1197. doi:10.1001/jamainternmed.2014.1532

Estimating Overdiagnosis in Lung Cancer Screening

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JAMA Intern Med. 2014;174(7):1197-1198. doi:10.1001/jamainternmed.2014.1535

Estimating Overdiagnosis in Lung Cancer Screening

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JAMA Intern Med. 2014;174(7):1198. doi:10.1001/jamainternmed.2014.1546

Estimating Overdiagnosis in Lung Cancer Screening—Reply

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JAMA Intern Med. 2014;174(7):1198-1199. doi:10.1001/jamainternmed.2014.1525

Percutaneous Coronary Intervention vs Medical Treatment in Stable AnginaThe Never-Ending Story

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JAMA Intern Med. 2014;174(7):1199-1200. doi:10.1001/jamainternmed.2014.1529

Supratherapeutic International Normalized Ratios in Warfarin-Treated Patients Who Receive a Highly Potentiating Antimicrobial Course

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JAMA Intern Med. 2014;174(7):1200. doi:10.1001/jamainternmed.2014.1615

Supratherapeutic International Normalized Ratios in Warfarin-Treated Patients Who Receive a Highly Potentiating Antimicrobial Course—Reply

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JAMA Intern Med. 2014;174(7):1200-1201. doi:10.1001/jamainternmed.2014.1589

Gabapentin Treatment for Alcohol Dependence

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JAMA Intern Med. 2014;174(7):1201. doi:10.1001/jamainternmed.2014.1618

Gabapentin Treatment for Alcohol Dependence—Reply

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JAMA Intern Med. 2014;174(7):1201-1202. doi:10.1001/jamainternmed.2014.1591

We Have Strict Statutes and Most Biting Laws

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JAMA Intern Med. 2014;174(7):1202. doi:10.1001/jamainternmed.2014.767

We Have Strict Statutes and Most Biting Laws—Reply

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JAMA Intern Med. 2014;174(7):1202-1203. doi:10.1001/jamainternmed.2014.764

We Have Strict Statutes and Most Biting Laws—Reply

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JAMA Intern Med. 2014;174(7):1203. doi:10.1001/jamainternmed.2014.765

Sexual Activity in Midlife Women and Beyond

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JAMA Intern Med. 2014;174(7):1203-1204. doi:10.1001/jamainternmed.2014.1621

Sexual Activity in Midlife Women and Beyond

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JAMA Intern Med. 2014;174(7):1204. doi:10.1001/jamainternmed.2014.1627

Sexual Activity in Midlife Women and Beyond

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JAMA Intern Med. 2014;174(7):1204-1205. doi:10.1001/jamainternmed.2014.2606

Sexual Activity in Midlife Women and Beyond—Reply

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JAMA Intern Med. 2014;174(7):1205. doi:10.1001/jamainternmed.2014.1592
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
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JAMA Intern Med. 2014;174(7):1020. doi:10.1001/jamainternmed.2013.10661
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