Vijan et al examine how treatment burden affects the benefits of intensive vs moderate glycemic control in patients with type 2 diabetes mellitus.
Baker and colleagues set out to determine whether a multifaceted intervention increases adherence to annual fecal occult blood testing compared with usual care. In their Invited Commentary, Green and Coronado further explore the topic of increased testing adherence among priority populations.
Albrecht et al estimate the risk of thrombotic and hemorrhagic events associated with warfarin therapy resumption following traumatic brain injury.
Rodriguez and colleagues examine the risk of incident cardiovascular events among participants with hypertension according to systolic blood pressure levels of 140 mm Hg or higher or 120 to 139 mm Hg relative to an SBP lower than 120 mm Hg. In his Invited Commentary, James expands on the importance of delivering the right care to the right patients.
Lee and colleagues determine whether statin use is associated with physical activity, longitudinally and cross-sectionally. Golomb provides and Invited Commentary.
Neuman et al describe patterns and predictors of mortality and functional decline in activities of daily living (ADLs) among nursing home residents after hip fracture. Ko and Morrison provide an Invited Commentary.
Austad and colleagues set out to determine whether there is an association between medical trainees’ interactions with pharmaceutical promotion and their preferences in medication use. Ross elucidates in the Editor’s Note.
Cunningham examines whether patients with high levels of engagement during medical encounters are more likely to receive advice and counseling about smoking compared with less engaged patients.
Preston and colleagues determine the association between 5α-reductase inhibitor use and development of high-grade or lethal prostate cancer.
Bonica et al analyze physicians’ campaign contributions from 1991 through 2012 to Republican and Democratic candidates in presidential and congressional races and to partisan organizations, including party committees and super political action committees.
Brinkman et al determine whether preoperative β-blocker use within 24 hours of coronary artery bypass grafting (CABG) surgery is associated with reduced perioperative mortality in a contemporary sample of patients. See also the Invited Commentary by Shahian.
Stergiopoulos and Brown compare genotype-guided initial dosing of warfarin and its analogues with clinical dosing protocols. See also the Invited Commentary by Kazi and Hlatky.
Zusterzeel and colleagues evaluate whether women with left bundle branch block benefit from cardiac resynchronization therapy defibrillators at a shorter QRS duration than men. In their Invited Commentary, Merz and Regitz-Zagrosek further explore the case for sex-specific interventions.
Nelson et al create an index that measures the extent of patient-centered medical home implementation, describe variation in implementation, and examine the association between the implementation index and key outcomes. See also the invited commentary by Baron.
Fröhlich et al determine the effect on long-term survival of using fractional flow reserve and intravascular US during percutaneous coronary intervention (PCI). They performed a cohort study based on the pan-London (United Kingdom) PCI registry. The primary end point was all-cause mortality at a median of 3.3 years. See the Invited Commentary by Malhotra.
Liebschutz and coauthors examine buprenorphine administration during medical hospitalization and linkage to office-based treatment.
Peritz et al report a case of an asymptomatic college athlete whose potential diagnosis of left ventricular noncompaction was first discovered on a preparticipation physical examination.
Gaines and colleagues highlight health and safety concerns for people traveling to these events in Brazil so that health care practitioners can better prepare travelers before they travel and more effectively diagnose and treat travelers after they return.
Onuoha et al develop a “top-five” list of unnecessary medical services in anesthesiology by undertaking a multistep survey of anesthesiologists, most of whom were in academic practice, and a consequent iterative process with the committees of the American Society of Anesthesiologists.