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February 2017 - January 1908

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October 1, 2015, Vol 175, No. 10, Pages 1599-1729

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2015;175(10):1599-1601. doi:10.1001/jamainternmed.2014.5089
Viewpoint

e-Cigarettes—The Roles of Regulation and Clinicians

Abstract Full Text
JAMA Intern Med. 2015;175(10):1603-1604. doi:10.1001/jamainternmed.2015.4436

This Viewpoint emphasizes the need for final FDA regulations for e-cigarettes to address product design, flavors, and marketing that appeal to younger individuals.

Perspective

When Knowing More About a Patient Enables Us to Do Less

Abstract Full Text
JAMA Intern Med. 2015;175(10):1605-1606. doi:10.1001/jamainternmed.2015.4219

An Injudicious Request—Performing a Test That Is Not Indicated

Abstract Full Text
JAMA Intern Med. 2015;175(10):1606-1607. doi:10.1001/jamainternmed.2015.4387
Original Investigation

Treatment of Vitamin D Insufficiency in Postmenopausal WomenA Randomized Clinical Trial

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2015;175(10):1612-1621. doi:10.1001/jamainternmed.2015.3874

This randomized clinical trial reports that high-dose cholecalciferol in postmenopausal women with low 25-hydroxyvitamin D levels had a small effect on calcium absorption and no significant effects on bone mineral density, muscle function, or falls.

Effect of Discontinuation of Antihypertensive Treatment in Elderly People on Cognitive Functioning—the DANTE Study LeidenA Randomized Clinical Trial

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2015;175(10):1622-1630. doi:10.1001/jamainternmed.2015.4103

This randomized clinical trial assesses whether discontinuing antihypertensive treatment improves cognitive, psychological, and general daily functioning in a population of elderly individuals with mild cognitive impairment and without serious cardiovascular disease.

A Study of the First Year of the End-of-Life Clinic for Physician-Assisted Dying in the Netherlands

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1633-1640. doi:10.1001/jamainternmed.2015.3978

This study reports that physicians in the Netherlands have more reservations about less common reasons that patients request euthanasia and physician-assisted suicide, such as psychological conditions and being tired of living, than the End-of-Life Clinic medical staff.

Effect of Florida’s Prescription Drug Monitoring Program and Pill Mill Laws on Opioid Prescribing and Use

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1642-1649. doi:10.1001/jamainternmed.2015.3931

This comparative interrupted time-series analyses used IMS Health LifeLink LRx data to quantify the effect of Florida’s Prescription Drug Monitoring Program and pill mill laws on overall and high-risk opioid prescribing and use.

Service Delivery and Patient Outcomes in Ryan White HIV/AIDS Program–Funded and –Nonfunded Health Care Facilities in the United States

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1650-1659. doi:10.1001/jamainternmed.2015.4095

This population-based study looks at the distinction between services provided as well as clinical outcomes of HIV-infected patients in facilities with funding from the Ryan White HIV/AIDS Program vs those without such funding.

Health Care Professionals’ Responses to Religious or Spiritual Statements by Surrogate Decision Makers During Goals-of-Care Discussions

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1662-1669. doi:10.1001/jamainternmed.2015.4124

This qualitative study uses audio recordings of conversations between patients’ surrogate decision makers and health care professionals in the intensive care unit to characterize the frequency of and professional responses to religious or spiritual statements.

Modeling the Health Effects of Expanding e-Cigarette Sales in the United States and United KingdomA Monte Carlo Analysis

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1671-1680. doi:10.1001/jamainternmed.2015.4209

This modeling study uses a Monte Carlo analysis to estimate the range of potential health effects that increased promotion and use of e-cigarettes might have on the US population.

Trends in Medicaid Reimbursements for Insulin From 1991 Through 2014

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1681-1687. doi:10.1001/jamainternmed.2015.4338

This study found that between 1991 and 2014, there was an upward trend in Medicaid payments for insulin products regardless of formulation, duration of action, and whether the product was patented, which suggests a lack of price competition for this class of medications.

Invited Commentary

A Discontinuation Trial of Antihypertensive TreatmentThe Other Side of the Story

Abstract Full Text
JAMA Intern Med. 2015;175(10):1630-1632. doi:10.1001/jamainternmed.2015.4309

Euthanasia in Belgium and the NetherlandsOn a Slippery Slope?

Abstract Full Text
JAMA Intern Med. 2015;175(10):1640-1641. doi:10.1001/jamainternmed.2015.4086

The Future of the Ryan White HIV/AIDS Program

Abstract Full Text
JAMA Intern Med. 2015;175(10):1660-1661. doi:10.1001/jamainternmed.2015.4724

Religion, Spirituality, and the Intensive Care UnitThe Sound of Silence

Abstract Full Text
JAMA Intern Med. 2015;175(10):1669-1670. doi:10.1001/jamainternmed.2015.4471

Guiding the Guardians and Other Participants in Shared Decision Making

Abstract Full Text
JAMA Intern Med. 2015;175(10):1691-1692. doi:10.1001/jamainternmed.2015.3968

Closing the Treatment Gap for Cardiac Rehabilitation

Abstract Full Text
JAMA Intern Med. 2015;175(10):1702-1703. doi:10.1001/jamainternmed.2015.3827

Ensuring a Diverse Physician WorkforceProgress but More to Be Done

Abstract Full Text
JAMA Intern Med. 2015;175(10):1708-1709. doi:10.1001/jamainternmed.2015.4333
Editor's Note

How Much Vitamin D Is Enough?

Abstract Full Text
free access
JAMA Intern Med. 2015;175(10):1621. doi:10.1001/jamainternmed.2015.3937
Special Communication

Guardianship and End-of-Life Decision Making

Abstract Full Text
JAMA Intern Med. 2015;175(10):1687-1691. doi:10.1001/jamainternmed.2015.3956

This review of US statutes and legal cases concerning guardianship of impaired adults seeks to provide multidisciplinary guidance to physicians and guardians about end-of-life treatment decisions.

From The JAMA Network

Risk of Cardiovascular Implantable Electronic Device Malfunction With Radiation TherapyLocation, Dose, or Energy?

Abstract Full Text
JAMA Intern Med. 2015;175(10):1698-1699. doi:10.1001/jamainternmed.2015.4128

This commentary on a recently published article from the JAMA Network places in context findings on risks of malfunction in cardiovascular implantable electronic devices during radiation therapy for cancer.

Teachable Moment

Optimizing the Safe Use of Direct Oral Anticoagulants in Older PatientsA Teachable Moment

Abstract Full Text
JAMA Intern Med. 2015;175(10):1608-1609. doi:10.1001/jamainternmed.2015.3589

While direct oral anticoagulants (DOACs) hold some advantages over vitamin K antagonists, DOAC adverse effects, including bleeding, present a clinical challenge in frail older patients.

Preoperative Stress Tests—Superfluous Investigations Resulting in Excessive Treatment DelayA Teachable Moment

Abstract Full Text
JAMA Intern Med. 2015;175(10):1610-1611. doi:10.1001/jamainternmed.2015.4420

This case report uses the example of an older patient undergoing hip fracture surgery to discuss judicious use of preoperative testing.

Challenges in Clinical Electrocardiography

A Case of P-Wave MimicryCherchez le P

Abstract Full Text
JAMA Intern Med. 2015;175(10):1693-1694. doi:10.1001/jamainternmed.2015.3342

Test your knowledge with an electrocardiogram quiz case involving P-wave mimicry.

ST-Segment Elevation Interpretation on ElectrocardiogramTo Cath or Not to Cath?

Abstract Full Text
JAMA Intern Med. 2015;175(10):1695-1697. doi:10.1001/jamainternmed.2015.3989
Research Letter

Participation in Cardiac Rehabilitation Programs Among Older Patients After Acute Myocardial Infarction

Abstract Full Text
free access
JAMA Intern Med. 2015;175(10):1700-1702. doi:10.1001/jamainternmed.2015.3819

This analysis of clinical data linked to Medicare claims finds the cardiac rehabilitation rate for older patients after acute myocardial infarction is low in the United States and suggests efforts be made for increasing referrals, and addressing attendance barriers, to rehabilitation sessions.

Comparison of the Expression and Granting of Requests for Euthanasia in Belgium in 2007 vs 2013

Abstract Full Text
free access
JAMA Intern Med. 2015;175(10):1703-1706. doi:10.1001/jamainternmed.2015.3982

This study examined the shifts in the expression and granting of euthanasia requests between 2007 and 2013 and the reasons that physicians granted or denied these requests.

Diversity in Graduate Medical Education in the United States by Race, Ethnicity, and Sex, 2012

Abstract Full Text
free access
JAMA Intern Med. 2015;175(10):1706-1708. doi:10.1001/jamainternmed.2015.4324

In this data analysis, graduate medical education diversity was assessed by race, ethnicity, and sex in 2012.

Undermeasuring Overuse—An Examination of National Clinical Performance Measures

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1709-1711. doi:10.1001/jamainternmed.2015.4025

This data analysis identified outpatient and emergency department process measures to determine to what extent the measures preferentially target underuse vs overuse.

Urinalysis Orders Among Patients Admitted to the General Medicine Service

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1711-1713. doi:10.1001/jamainternmed.2015.4036

This cohort study of appropriate orders for urinalysis determines whether overuse of urinalysis contributes to misdiagnosis and excessive use of antibiotics among elderly patients admitted to the emergency department of a tertiary care center.

Symptom Burden Among Patients Who Were Hospitalized for Heart Failure

Abstract Full Text
free access
JAMA Intern Med. 2015;175(10):1713-1715. doi:10.1001/jamainternmed.2015.3871

This study evaluated the spectrum of symptoms, improvement in symptoms after discharge, and perceptions of palliative care among patients who were hospitalized for heart failure.

Statin Use in Very Elderly Individuals, 1999-2012

Abstract Full Text
free access
JAMA Intern Med. 2015;175(10):1715-1716. doi:10.1001/jamainternmed.2015.4302

This survey investigates the use of statins in individuals older than 79 years by vascular disease.

Rates of Kidney Transplantation From Living and Deceased Donors for Blacks and Whites in the United States, 1998 to 2011

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1716-1718. doi:10.1001/jamainternmed.2015.4530

This database review found that by 2010 the incidence of kidney transplantation for black and white patients with end-stage renal disease was equivalent, but kidney transplants from living donors were 43.2% for whites and only 22.2% for blacks.

Comment & Response

The Link Between Sauna Bathing and Mortality May Be Noncausal

Abstract Full Text
JAMA Intern Med. 2015;175(10):1718. doi:10.1001/jamainternmed.2015.3426

The Link Between Sauna Bathing and Mortality May Be Noncausal

Abstract Full Text
JAMA Intern Med. 2015;175(10):1718-1719. doi:10.1001/jamainternmed.2015.3429

The Link Between Sauna Bathing and Mortality May Be Noncausal—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(10):1719. doi:10.1001/jamainternmed.2015.3432

Study Design for Vitamin D Randomized Clinical Trials

Abstract Full Text
JAMA Intern Med. 2015;175(10):1720. doi:10.1001/jamainternmed.2015.3765

Study Design for Vitamin D Randomized Clinical Trials—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(10):1720-1721. doi:10.1001/jamainternmed.2015.3768

Another Report of Familial Spontaneous Coronary Artery Dissection

Abstract Full Text
JAMA Intern Med. 2015;175(10):1721. doi:10.1001/jamainternmed.2015.3824

Another Report of Familial Spontaneous Coronary Artery Dissection—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(10):1721-1722. doi:10.1001/jamainternmed.2015.3830

Physical Function and Hospital Readmissions

Abstract Full Text
JAMA Intern Med. 2015;175(10):1722. doi:10.1001/jamainternmed.2015.3922

Physical Function and Hospital Readmissions—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(10):1723. doi:10.1001/jamainternmed.2015.3925

Vitamin D Supplements and the Risk of Falls

Abstract Full Text
JAMA Intern Med. 2015;175(10):1723-1724. doi:10.1001/jamainternmed.2015.3962

Vitamin D Supplements and the Risk of Falls—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(10):1724. doi:10.1001/jamainternmed.2015.3965

Selecting the Optimal Design for Drug Discontinuation Trials in a Setting of Advanced, Life-Limiting Illness

Abstract Full Text
JAMA Intern Med. 2015;175(10):1724-1725. doi:10.1001/jamainternmed.2015.3997

Selecting the Optimal Design for Drug Discontinuation Trials in a Setting of Advanced, Life-Limiting Illness

Abstract Full Text
JAMA Intern Med. 2015;175(10):1725. doi:10.1001/jamainternmed.2015.4000

Selecting the Optimal Design for Drug Discontinuation Trials in a Setting of Advanced, Life-Limiting Illness—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(10):1725. doi:10.1001/jamainternmed.2015.4003

Diet and Colorectal Cancer Incidence

Abstract Full Text
JAMA Intern Med. 2015;175(10):1726-1727. doi:10.1001/jamainternmed.2015.4016

Diet and Colorectal Cancer Incidence—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(10):1727. doi:10.1001/jamainternmed.2015.4019

Noninvasive Testing in Patients With Chest Pain

Abstract Full Text
JAMA Intern Med. 2015;175(10):1727. doi:10.1001/jamainternmed.2015.4152

Noninvasive Testing in Patients With Chest Pain—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(10):1728-1729. doi:10.1001/jamainternmed.2015.4149
Correction

Error in Figure

Abstract Full Text
free access
JAMA Intern Med. 2015;175(10):1729. doi:10.1001/jamainternmed.2015.5659
Images From Our Readers

Sunset

Abstract Full Text
JAMA Intern Med. 2015;175(10):1632. doi:10.1001/jamainternmed.2015.4089
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
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JAMA Intern Med. 2015;175(10):1602. doi:10.1001/jamainternmed.2014.5090
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