I read with interest the article by Ovbiagele.1 A number of participants have metabolic syndrome. I was wondering if the author is aware of many medications that deteriorate renal function2- 4 and that are widely prescribed in such a population, such as angiotensin-converting enzyme inhibitors, rosuvastatin, nonsteroidal anti-inflammatory drugs (including high doses of aspirin). Failure to ask patients about such drugs would bias the results of the study.
Kittisupamongkol W. Medications Impair Kidney Function in Stroke Population. Arch Neurol. 2009;66(3):416-421. doi:10.1001/archneurol.2008.571