We thank Schlesinger and colleagues for their interest in our study on dopamine agonist withdrawal syndrome (DAWS) in Parkinson disease.1 They describe the successful use of apomorphine injections to control short-term withdrawal symptoms in 3 of 5 patients who discontinued use of a dopamine agonist prior to DBS surgery for Parkinson disease. It is unclear whether these transient withdrawal symptoms might have progressed to DAWS if dopamine agonist therapy had not been restarted postoperatively.
Nirenberg MJ, Rabinak CA. Dopamine Agonist Withdrawal Syndrome: The Apomorphine Solution—Reply. Arch Neurol. 2010;67(9):1155-1156. doi:10.1001/archneurol.2010.221