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Images in Neurology
Aug 2011

The Many Faces of Central Nervous System Tuberculosis

Arch Neurol. 2011;68(8):1078. doi:10.1001/archneurol.2011.169

Central nervous system involvement is the most devastating form of tuberculosis. A high mortality and severe neurological sequelae1 are consequences of a delayed diagnosis due to heterogeneous clinical and neuroimaging manifestations. We present some central nervous system tuberculosis cases; all patients had histopathologic or culture evidence of tuberculous bacilli. Gadolinium-enhanced magnetic resonance imaging (MRI) findings ranged from focal leptomeningitis to tuberculomas (Figure). Four patients developed new lesions under antituberculous treatment for tuberculous meningitis.

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