Central nervous system involvement is the most devastating form of tuberculosis. A high mortality and severe neurological sequelae1 are consequences of a delayed diagnosis due to heterogeneous clinical and neuroimaging manifestations. We present some central nervous system tuberculosis cases; all patients had histopathologic or culture evidence of tuberculous bacilli. Gadolinium-enhanced magnetic resonance imaging (MRI) findings ranged from focal leptomeningitis to tuberculomas (Figure). Four patients developed new lesions under antituberculous treatment for tuberculous meningitis.
Cárdenas G, Soto-Hernández JL. The Many Faces of Central Nervous System Tuberculosis. Arch Neurol. 2011;68(8):1078. doi:10.1001/archneurol.2011.169