Aug 2012

Seronegative Myasthenia GravisThe Importance of Clusters of Acetylcholine Receptors

Author Affiliations

Author Affiliation: Neurological Institute, New York, New York.

Arch Neurol. 2012;69(8):965-966. doi:10.1001/archneurol.2012.749

In the current issue of the Archives, Jacob and colleagues1 update details of the pathogenesis of myasthenia gravis (MG), which may be the prototype of all human autoimmune diseases. The modern story could have started with John A. Simpson (1922-2009), a Scottish neurologist and pioneer in electromyography. He published 2 reviews that summarized the evidence.2,3