Author Affiliations: Department of Internal Medicine–Geriatrics, Wake Forest School of Medicine, Winston-Salem, North Carolina (Dr Baker); and Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Dr Vitiello).
Recently, we described the results of a controlled, 5-month trial of growth hormone–releasing hormone (GHRH) for cognitively normal older adults and adults with mild cognitive impairment that demonstrated favorable effects on cognition.1 This study, for which cognitive outcomes were primary, is the sequel of an earlier study that focused on GHRH effects on sleep, while analysis of cognitive response to treatment was secondary.
Baker LD, Vitiello MV. Growth Hormone–Releasing Hormone Improves Cognitive Function in Older Adults: Sleep On It—Reply. JAMA Neurol. 2013;70(4):529-530. doi:10.1001/jamaneurol.2013.2064