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April 2013

Growth Hormone–Releasing Hormone Improves Cognitive Function in Older Adults: Sleep On It—Reply

Author Affiliations

Author Affiliations: Department of Internal Medicine–Geriatrics, Wake Forest School of Medicine, Winston-Salem, North Carolina (Dr Baker); and Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Dr Vitiello).

JAMA Neurol. 2013;70(4):529-530. doi:10.1001/jamaneurol.2013.2064

In reply

Recently, we described the results of a controlled, 5-month trial of growth hormone–releasing hormone (GHRH) for cognitively normal older adults and adults with mild cognitive impairment that demonstrated favorable effects on cognition.1 This study, for which cognitive outcomes were primary, is the sequel of an earlier study that focused on GHRH effects on sleep, while analysis of cognitive response to treatment was secondary.

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