Author Affiliation: Division of Child Neurology, Nationwide Children's Hospital, Columbus, Ohio.
A 16-year-old previously healthy male had a generalized seizure. In the emergency department, he was combative, requiring administration of lorazepam and haloperidol. A noncontrast computed tomographic scan of the head (Figure 1) was suspicious for a large vascular malformation involving the left temporal, parietal, and occipital lobes. The neurological examination was significant for impaired word repetition ability and truncal ataxia without dysmetria or dysdiadokinesia. The ataxia resolved over 24 hours and was assumed to be secondary to medications. The young man's brain magnetic resonance imaging revealed a large arteriovenous malformation (AVM) involving the aforementioned lobes with arterial supply from the left middle cerebral artery and the left posterior cerebral artery (Figure 2). The consultant neurosurgeon indicated that the lesion was not amenable to surgical treatment owing to almost complete involvement of the left hemisphere and the lesion's dual supply from the anterior and posterior circulations. The patient was prescribed antiepilepsy medication and has remained seizure free 18 months out.
McKinney JL. Large Arteriovenous Malformation in an Adolescent Presenting With First Seizure. JAMA Neurol. 2013;70(6):798. doi:10.1001/jamaneurol.2013.1945