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A 50-year-old man with a history of hyperlipidemia presented with worsening headache following a motor vehicle crash that had caused a closed head injury. He had no neurologic deficits and optic discs were difficult to appreciate. Hypercoagulable panel results (including antithrombin III, factor V Leiden, prothrombin G20210A mutation, protein C, protein S, lupus anticoagulant, anticardiolipin antibodies, and β-2 microglobulin) were unremarkable. Computed tomographic head noncontrast on admission had demonstrated possible cerebral venous thrombosis, and computed tomographic venography was performed to confirm this diagnosis (Figure 1).
Nelson S, Ho B. Extensive Cerebral Venous Thrombosis. JAMA Neurol. 2013;70(8):1070-1071. doi:10.1001/jamaneurol.2013.1952