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In Reply We appreciate the insightful commentary from our colleagues, Schlimp et al, regarding our article on cerebral air embolism.1 Despite a lack of prospective data, emergent therapies focus on Trendelenburg patient positioning and hyperbaric oxygen treatment (HBOT). Moreover, the precise pathophysiology of cerebral venous air embolization has yet to be delineated. Nonetheless, the literature does provide a number of retrospective clinical observations and animal model studies on which we base our clinical decisions. Current therapies are relatively noninvasive, with low potential for major complications.
Lai D, Jadhav AP. Cerebral Venous Air Embolism—Reply. JAMA Neurol. 2014;71(2):243-244. doi:10.1001/jamaneurol.2013.5556