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Diffusion-weighted imaging (DWI) has revealed the reversal of often sizeable damage due to brainstem lesions in patients treated within 4.5 hours, and this reversibility of damage was strongly associated with early neurological improvement.1 In posterior circulation stroke, the reversibility of damage due to a DWI-detected lesion is poorly documented after intravenous thrombolysis2 or intra-arterial therapy.3,4 We report a case of vertebrobasilar stroke mechanically recanalized 4.5 hours after symptom onset that revealed substantial reversal of early ischemic damage to the brainstem on DWI scans.
Gory B, Ritzenthaler T, Riva R, Nighoghossian N, Turjman F. Reversibility of Brainstem Damage After a Mechanical Thrombectomy. JAMA Neurol. 2014;71(5):646-647. doi:10.1001/jamaneurol.2013.5574