To the Editor We read with interest the article by Shu et al1 and we would like to make the following observations on the basis of our personal experience.
Medulloblastoma is a primitive neuroectodermal tumor and about 50% of these tumors occur in children aged younger than 5 years, whereas they are rare in adolescents and young adults. Medulloblastoma behaves differently in adults than in children and is identified as a different biological and clinical entity. It exhibits a higher proportion of desmoplastic histologic characteristics than childhood medulloblastoma and shows a higher incidence within the cerebellar hemispheres, thus featuring different proliferative and apoptotic indices and having a tendency for late relapse.2
Gelabert-González M, Arán-Echabe E. Medulloblastoma and Dizziness. JAMA Neurol. 2014;71(6):801. doi:10.1001/jamaneurol.2014.173