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Comment & Response
March 2015

Deep Brain Stimulation for Parkinson Disease in Elderly Individuals

Author Affiliations
  • 1School of Clinical Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, England
  • 2Department of Surgery, University of Cambridge, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, England
JAMA Neurol. 2015;72(3):367-368. doi:10.1001/jamaneurol.2014.4222

To the Editor We read with great interest the article by DeLong et al1 regarding deep brain stimulation (DBS), an established surgical solution for the motor symptoms of Parkinson disease.2 They conducted a large nonrandomized clinical trial in which they demonstrated that comparable results are achieved with DBS in patients older than 75 years, contrary to popular belief. We consider this study a significant milestone: it lucidly shows us that despite our preconceptions, we can achieve decent results in elderly individuals for the treatment of PD and, more broadly, in the neurosurgical domain. However, before this study is used as a model for future trials, we would like to make 3 methodological observations.

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