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Comment & Response
May 2015

Defining the Eye-of-the-Tiger Sign—Reply

Author Affiliations
  • 1Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
  • 2Govind Ballabh Pant Hospital, New Delhi, India
  • 3Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania
  • 4Department of Neurology, Penn State College of Medicine, Hershey, Pennsylvania

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JAMA Neurol. 2015;72(5):606-607. doi:10.1001/jamaneurol.2015.0147

In Reply We appreciate the comments by Sethi et al regarding our article.1 The patient was referred with a possible diagnosis of neurodegeneration with brain iron accumulation (which we were, as noted, erroneously referring to as neuroferritinopathy), and the fundamental message of our article1 was that neurologists have to be careful about this diagnosis especially when the abnormality is unilateral.

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