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Comment & Response
August 2016

Nitric Oxide Deficiency Triggering Strokelike Episodes—Reply

Author Affiliations
  • 1The University of Texas Medical School at Houston
JAMA Neurol. 2016;73(8):1030. doi:10.1001/jamaneurol.2016.1649

In Reply We thank Finsterer and Zarrouk-Mahjoub for their interest in our article1 and direct them to our introduction to address most of their concerns. They mention that there are examples in the literature where patients experiencing a strokelike episode completely recover. We agree with this statement. Our article stated that “recovery from strokelike episodes in MELAS [mitochondrial encephalomyopathy with lactic acidosis and strokelike episodes] is typically rapid and complete early in the disease.”1

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