Intracerebral hemorrhage (ICH) is a common and deadly type of stroke, with high rates of morbidity and mortality (40%-50% in most series).1,2 There are several well-described and validated risk factors and diseases that increase the risk of ICH, including race, hypertension, use of anticoagulants, amyloid angiopathy, renal insufficiency, thrombolytic therapy, and drug abuse.3 However, not all ICHs are associated with one of these risk factors. This suggests that there might be some other modifying factors involved.
Alberts MJ, Sarode R. Association Between Serum Calcium Level and the Size and Expansion of Intracerebral Hemorrhage. JAMA Neurol. 2016;73(11):1276-1277. doi:10.1001/jamaneurol.2016.3070