Views 126
Citations 0
Comment & Response
September 19, 2016

Diagnosing Traumatic Encephalopathy Syndrome

Author Affiliations
  • 1Neurosurgery, Hennepin County Medical Center, Minneapolis, Minnesota

Copyright 2016 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Neurol. Published online September 19, 2016. doi:10.1001/jamaneurol.2016.2802

To the Editor We agree with Reams and colleagues’ review1 finding that because mislocalized phosphorylated tau is neither pathognomic nor causative for clinical neurodegenerative disease, efforts focusing on identification of chronic traumatic encephalopathy in living people are not clinically useful. Chronic traumatic encephalopathy is present in equal incidence in normal healthy elderly individuals as in people with neurodegenerative disease.2 It is a pathologic finding with no clinical correlate.3,4

First Page Preview View Large
First page PDF preview
First page PDF preview