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Comment & Response
December 2016

Trends in the Incidence of Parkinson Disease—Reply

Author Affiliations
  • 1Division of Epidemiology, Departments of Health Sciences Research and Neurology, College of Medicine, Mayo Clinic, Rochester, Minnesota
  • 2Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, Minnesota
JAMA Neurol. 2016;73(12):1498-1499. doi:10.1001/jamaneurol.2016.3847

In Reply We appreciate the comments expressed by Darweesh and colleagues and by Macerollo and Chen concerning our article on time trends for Parkinson disease (PD) in Olmsted County, Minnesota.1 Both groups of authors challenged the attribution of the increasing trend in the incidence of PD to a declining trend in cigarette smoking over time. They also called for an international collaborative research effort to identify risk and protective factors for PD.

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