A 63-year-old man presented with a 4-year history of insidious onset and gradual progression of visual symptoms including right homonymous hemianopsia, alexia, and simultanagnosia with preserved memory. Magnetic resonance imaging, perfusion single-photon emission computed tomography, and fluorodeoxyglucose positron emission tomographic scans revealed strikingly asymmetric left parieto-occipital abnormality. Neuropsychological testing was performed. The differential diagnosis, pathologic findings, genetic testing results, and diagnosis are discussed.
Mitchell SB, Lucente D, Larvie M, Cobos MI, Frosch M, Dickerson BC. A 63-Year-Old Man With Progressive Visual Symptoms. JAMA Neurol. 2017;74(1):114-118. doi:10.1001/jamaneurol.2016.2210