In Parkinson disease (PD), the abnormal aggregation of α-synuclein occurs in multiple peripheral organs along autonomic neuronal processes1,2 and is thought to underlie some nonmotor symptoms. Here we report the presence of α-synuclein deposits in the gonadal tissue of 2 patients with PD.
Garrido A, Aldecoa I, Gelpi E, Tolosa E. Aggregation of α-Synuclein in the Gonadal Tissue of 2 Patients With Parkinson Disease. JAMA Neurol. Published online March 13, 2017. doi:10.1001/jamaneurol.2016.6155