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March 1968

Neurological Syndromes Associated With Cervical and Craniocervical Anomalies

Author Affiliations

Edinburgh; London
From Queen Alexandra Military Hospital, Millbank, London, England. Doctor Clark is now at the Gastrointestinal Research Laboratories, Philadelphia General Hospital.

Arch Neurol. 1968;18(3):241-247. doi:10.1001/archneur.1968.00470330031002

CONGENITAL abnormalities of the cervical region have long been recognized, the first report being that of Rokitansky in 1846.1

Since then, there have been many accounts, but they have mainly described the anatomical defects. Only a few clinical reports have been published in detail since Homen2 established a correlation between malformations in this region and neurological syndromes. Spillane et al3 published their review, and further cases were reported by Bharucha and Dastur.4 Both these reports deal mainly with the radiological or associated pathological features of the disease and relate them secondarily to the clinical features.

Garcin and Oeconomos5 reviewed 114 patients reported in the literature and added 18 of their own. They presented a complete clinical and radiological study, but, unfortunately, this review is not readily available to the practicing physician.

We report 13 patients with bony abnormalities of the cervical region accompanied by

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