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Article
December 1968

STUDIES ON PSEUDOHYPERTROPHIC MUSCULAR PARALYSIS OR MYOSCLEROTIC PARALYSIS

Arch Neurol. 1968;19(6):629-636. doi:10.1001/archneur.1968.00480060099015
Abstract

A. Definition and Naming of the Disease The disease I will describe is characterized principally by: (1) weakness of movements, usually settling at first in the muscles of the lower extremities and the lumbar spine, then spreading to the upper extremities at the terminal stage and worsening at the same time until movement is abolished; (2) increase of volume either (ordinarily) in several of the paralyzed muscles or (exceptionally) in nearly all the paralyzed muscles; (3) hyperplasia of the interstitial connettive tissue of the paralyzed muscles, with an abundant production of fibrous tissue or of fatty vesicles in the more advanced stage.

I propose to call this disease pseudohyper-trophic muscular paralysis after its principal objective clinical signs or myosclerotic paralysis after its peripheral anatomic characteristics. These terms will be justified by studying the symptomatology and the pathologic anatomy in the living during the course of the disease. I prefer

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