Two examples of subdural hematoma complicating chronic intermittent dialysis are presented. The administration of anticoagulants seemed to play a significant role, but other factors such as biochemical changes caused by hemodialysis and renal disease may have contributed. Prolonged headache and the appearance of unilateral neurological signs were significant early warnings and helped to differ the presence of a hematoma from the more common neurological changes that sometimes accompany hemodialysis. Carotid angiography definitively established the diagnosis.
Bechar M, Lakke JPWF, van der Hem GK, Beks JWF, Penning L. Subdural Hematoma During Long-Term Hemodialysis. Arch Neurol. 1972;26(6):513–516. doi:10.1001/archneur.1972.00490120053005