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December 1972

Experimental Spinal Cord TraumaA Historical Review

Author Affiliations

From the Department of Surgery, Massachusetts General Hospital; and Harvard Medical School, Boston; and the departments of surgery and pathology, Northwestern University Medical School; and the Department of Neurosurgery, Chicago Wesley Memorial Hospital.

Arch Neurol. 1972;27(6):468-473. doi:10.1001/archneur.1972.00490180004003

A review of the literature on experimental spinal cord trauma indicates the advantages of using a reproducible and quantifiable form of injury. Studies to date indicate that contusion of the spinal cord, creating either transitory traumatic paraplegia or permanent traumatic paraplegia, results in structural, vascular, physiological, and biochemical changes, each of which may be altered by various treatment methods.