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Article
August 1975

Carcinoid MyopathySerotonin-Induced Muscle Weakness in Man?

Author Affiliations

FILMT
From the Department of Neurology, Section of Neurological Sciences, the London Hospital.

Arch Neurol. 1975;32(8):572-574. doi:10.1001/archneur.1975.00490500092014
Abstract

A myopathy, which improved with cyproheptadine hydrochloride therapy, developed in a patient with carcinoid syndrome of ten years' duration. Biopsy examination revealed advanced atrophy of type II muscle fibers, with type I fiber preponderance. Many of the small fibers had degenerated. Carcinoid myopathy may be due to excess circulating serotonin.

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